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Roger G. Deeley

Affiliations: 
Queen's University, Canada, Kingston, Ontario, Canada 
Area:
Biochemistry
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"Roger Deeley"
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Mian Gao grad student 2000 Queen's University, Canada
Max L. Tejada grad student 2000 Queen's University, Canada

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Trofimova DN, Deeley RG. (2018) Structural studies of Multidrug Resistance Protein 1 (MRP1) using "almost" cysless template. Drug Metabolism and Disposition: the Biological Fate of Chemicals
Qin L, Tam SP, Deeley RG. (2012) Effect of multiple cysteine substitutions on the functionality of human multidrug resistance protein 1 expressed in human embryonic kidney 293 cells: identification of residues essential for function. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 1403-13
Rosenberg MF, Oleschuk CJ, Wu P, et al. (2010) Structure of a human multidrug transporter in an inward-facing conformation. Journal of Structural Biology. 170: 540-7
Maeno K, Nakajima A, Conseil G, et al. (2009) Molecular basis for reduced estrone sulfate transport and altered modulator sensitivity of transmembrane helix (TM) 6 and TM17 mutants of multidrug resistance protein 1 (ABCC1). Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 1411-20
Conseil G, Rothnie AJ, Deeley RG, et al. (2009) Multiple roles of charged amino acids in cytoplasmic loop 7 for expression and function of the multidrug and organic anion transporter MRP1 (ABCC1). Molecular Pharmacology. 75: 397-406
Qin L, Zheng J, Grant CE, et al. (2008) Residues responsible for the asymmetric function of the nucleotide binding domains of multidrug resistance protein 1. Biochemistry. 47: 13952-65
Grant CE, Gao M, DeGorter MK, et al. (2008) Structural determinants of substrate specificity differences between human multidrug resistance protein (MRP) 1 (ABCC1) and MRP3 (ABCC3). Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 2571-81
Rothnie A, Conseil G, Lau AY, et al. (2008) Mechanistic differences between GSH transport by multidrug resistance protein 1 (MRP1/ABCC1) and GSH modulation of MRP1-mediated transport. Molecular Pharmacology. 74: 1630-40
Bandler PE, Westlake CJ, Grant CE, et al. (2008) Identification of regions required for apical membrane localization of human multidrug resistance protein 2. Molecular Pharmacology. 74: 9-19
Létourneau IJ, Nakajima A, Deeley RG, et al. (2008) Role of proline 1150 in functional interactions between the membrane spanning domains and nucleotide binding domains of the MRP1 (ABCC1) transporter. Biochemical Pharmacology. 75: 1659-69
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