Umesh R. Desai

1994-1996 Indian Institute of Technology Bombay, Mumbai, Maharashtra, India 
 1996-1998 University of Illinois at Chicago, Chicago, IL, United States 
 1998- Virginia Commonwealth University, Richmond, VA, United States 
Pharmaceutical Chemistry, Medicinal Chemistry, Biochemistry
"Umesh R. Desai"
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Girish K. Trivedi grad student 1985-1991 IIT Bombay
Robert J. Linhardt post-doc 1991-1993 University of Iowa
 (Professor, Department of Medicinal Chemistry, Virginia Commonwealth University, Richmond, VA)
Alexander M. Klibanov post-doc 1993-1994 MIT


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Samuel Holmes grad student 2019- VCU
Connor O'Hara grad student 2019- VCU
Rawan Fayyad grad student 2021- VCU
Ally Thompson grad student 2022- VCU
Gunnar T. Gunnarsson grad student 1998-2003 VCU
Junaid Afridi grad student 2003-2006 VCU
Brian Henry grad student 2005-2007 VCU
Arjun Raghuraman grad student 2003-2008 VCU
Chandravel Krishnasamy grad student 2003-2009 VCU
Jay N. Thakkar grad student 2011 VCU
J. Timothy King grad student 2006-2011 VCU
Rami Al-Horani grad student 2007-2011 VCU
Preetpal Singh Sidhu grad student 2007-2011 VCU
May Hamdy Abdel Aziz grad student 2013 VCU
Akul Mehta grad student 2008-2014 VCU
Rio Boothello grad student 2009-2014 VCU
Meghan Thompson grad student 2010-2015 VCU
Stephen Verespy grad student 2012-2016 VCU
Daniel Afosah grad student 2012-2017 VCU
Alhumaidi Alabbas grad student 2014-2018 VCU
Shravan Morla grad student 2015-2019 VCU
Rahaman Navaz Gangji grad student 2016-2020 VCU
John Chittum grad student 2018-2022 VCU
Elsamani Abdelfadiel grad student 2017-2023 VCU
S. Nehru Viji post-doc 2012- VCU
Balaji Nagarajan post-doc 2014- VCU
Rama Gunta post-doc 2019- VCU
Aiye Liang post-doc 2006-2011 VCU
Philip D. Mosier post-doc 2009-2011 VCU
Aurijit Sarkar post-doc 2012-2016 VCU
Jyothi Sistla post-doc 2016-2020 VCU
Ravikumar Ongolu post-doc 2017-2020 VCU


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Pradeep T Deota collaborator 2013-2018
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Holmes SG, Desai UR. (2023) Assessing Genetic Algorithm-Based Docking Protocols for Prediction of Heparin Oligosaccharide Binding Geometries onto Proteins. Biomolecules. 13
Pradhan AK, Modi J, Maji S, et al. (2023) Dual Targeting of the PDZ1 and PDZ2 Domains of MDA-9/Syntenin Inhibits Melanoma Metastasis. Molecular Cancer Therapeutics. OF1-OF13
Afosah DK, Fayyad RM, Puliafico VR, et al. (2023) Homogeneous, Synthetic, Non-Saccharide Glycosaminoglycan Mimetics as Potent Inhibitors of Human Cathepsin G. Biomolecules. 13
Sankaranarayanan NV, Sistla S, Nagarajan B, et al. (2023) Computational studies on glycosaminoglycan recognition of Sialyl transferases. Glycobiology
Abdelfadiel EI, Gunta R, Villuri BK, et al. (2023) Designing Smaller, Synthetic, Functional Mimetics of Sulfated Glycosaminoglycans as Allosteric Modulators of Coagulation Factors. Journal of Medicinal Chemistry. 66: 4503-4531
Kellogg GE, Cen Y, Dukat M, et al. (2023) Merging Cultures and Disciplines to Create a Drug Discovery Ecosystem at Virginia Commonwealth University: Medicinal Chemistry, Structural Biology, Molecular and Behavioral Pharmacology and Computational Chemistry. Slas Discovery : Advancing Life Sciences R & D
Ponnuraj N, Akbar H, Arrington JV, et al. (2023) The alphaherpesvirus conserved pUS10 is important for natural infection and its expression is regulated by the conserved Herpesviridae protein kinase (CHPK). Plos Pathogens. 19: e1010959
Morla S, Ravikumar O, O'Hara C, et al. (2023) Designing Synthetic, Sulfated Glycosaminoglycan Mimetics That Are Orally Bioavailable and Exhibiting Anticancer Activity. Journal of Medicinal Chemistry
Boothello RS, Sankaranarayanan NV, Sistla JC, et al. (2022) Glycan Modulation of Insulin-like Growth Factor-1 Receptor. Angewandte Chemie (International Ed. in English)
Holmes SG, Nagarajan B, Desai UR. (2022) 3--Sulfation induces sequence-specific compact topologies in heparan sulfate that encode a dynamic sulfation code. Computational and Structural Biotechnology Journal. 20: 3884-3898
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