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Kent Sugden

Affiliations: 
University of Montana, Missoula, MT 
Area:
Biochemistry
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"Kent Sugden"
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Parents

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Children

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Jonathan O. Speare grad student 2003 Univ. Montana
M. K. Hailer grad student 2006 Univ. Montana
Peter G. Slade grad student 2006 Univ. Montana

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Publications

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Shafirovich V, Kropachev K, Anderson T, et al. (2016) Base and Nucleotide Excision Repair of Oxidatively Generated Guanine Lesions in DNA. The Journal of Biological Chemistry
Gremaud JN, Martin BD, Sugden KD. (2010) Influence of substrate complexity on the diastereoselective formation of spiroiminodihydantoin and guanidinohydantoin from chromate oxidation. Chemical Research in Toxicology. 23: 379-85
Little LG, Sugden KD. (2009) Chromium-Induced DNA Damage and Repair Metal Complex-Dna Interactions. 463-489
Slade PG, Priestley ND, Sugden KD. (2007) Spiroiminodihydantoin as an oxo-atom transfer product of 8-oxo-2'-deoxyguanosine oxidation by chromium(V). Organic Letters. 9: 4411-4
Martin BD, Schoenhard JA, Hwang JM, et al. (2006) Ascorbate is a pro-oxidant in chromium-treated human lung cells. Mutation Research. 610: 74-84
O'Brien TJ, Mandel HG, Sugden KD, et al. (2005) Hypoxia impedes the formation of chromium DNA-adducts in a cell-free system. Biochemical Pharmacology. 70: 1814-22
Hailer MK, Slade PG, Martin BD, et al. (2005) Nei deficient Escherichia coli are sensitive to chromate and accumulate the oxidized guanine lesion spiroiminodihydantoin. Chemical Research in Toxicology. 18: 1378-83
Slade PG, Hailer MK, Martin BD, et al. (2005) Guanine-specific oxidation of double-stranded DNA by Cr(VI) and ascorbic acid forms spiroiminodihydantoin and 8-oxo-2'-deoxyguanosine. Chemical Research in Toxicology. 18: 1140-9
Hailer MK, Slade PG, Martin BD, et al. (2005) Recognition of the oxidized lesions spiroiminodihydantoin and guanidinohydantoin in DNA by the mammalian base excision repair glycosylases NEIL1 and NEIL2. Dna Repair. 4: 41-50
Sugden KD, Rigby KM, Martin BD. (2004) Oxidative activation of the human carcinogen chromate by arsenite: a model for synergistic metal activation leading to oxidative DNA damage. Toxicology in Vitro : An International Journal Published in Association With Bibra. 18: 741-8
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