Mark R. Philips, M.D.

Affiliations: 
1991- New York University, New York, NY, United States 
Area:
Cell Biology, Biochemistry
Website:
https://www.atthelimits.org/biographies/dr-mark-r-philips/
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Children

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Vi K. Chiu grad student 2002 NYU
Heidi H. Wiener grad student 2003 NYU
Trever G. Bivona grad student 2004 NYU
Latasha P. Wright grad student 2005 NYU
Wasif M. Abidi grad student 2007 NYU
Steven E. Quatela grad student 2007 NYU
Ian M. Ahearn grad student 2010 NYU
Pamela J. Sung grad student 2010 NYU
Joseph P. Wynne grad student 2011 NYU
Frederick D. Tsai grad student 2014 NYU
Mo Zhou grad student 2014 NYU
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Publications

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Ren JG, Xing B, Lv K, et al. (2023) RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia. The Journal of Clinical Investigation. 133
Kochen Rossi J, Nuevo-Tapioles C, Philips MR. (2023) Differential functions of the KRAS splice variants. Biochemical Society Transactions
García-España A, Philips MR. (2023) Origin and Evolution of RAS Membrane Targeting. Oncogene
Simanshu DK, Philips MR, Hancock JF. (2023) Consensus on the RAS dimerization hypothesis: Strong evidence for lipid-mediated clustering but not for G-domain-mediated interactions. Molecular Cell
Philips M, García-España A. (2023) Origin and evolution of RAS oncoprotein membrane targeting. Research Square
Liang D, Jiang L, Bhat SA, et al. (2023) Palmitoylation and PDE6δ regulate membrane-compartment-specific substrate ubiquitylation and degradation. Cell Reports. 42: 111999
Campbell SL, Philips MR. (2021) Post-translational modification of RAS proteins. Current Opinion in Structural Biology. 71: 180-192
Deng J, Thennavan A, Dolgalev I, et al. (2021) ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1 mutant lung cancer. Nature Cancer. 2: 503-514
Ahearn IM, Court HR, Siddiqui F, et al. (2021) NRAS is unique among RAS proteins in requiring ICMT for trafficking to the plasma membrane. Life Science Alliance. 4
Chen X, Yao H, Kashif M, et al. (2021) A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells. Elife. 10
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