Douglas Lowell Theobald, Ph.D.
Affiliations: | 2007- | Biochemistry | Brandeis University, Waltham, MA, United States |
Area:
Telomeres, molecular evolution, structural bioinformatics, superposition, rhodopsin, bacteriorhodopsin, lactate dehydrogenase, malate dehydrogenaseWebsite:
http://theobald.brandeis.edu/Google:
"Douglas Theobald"Cross-listing: Telomere and Telomerase Tree
Parents
Sign in to add mentor| Steve C. Schultz | grad student | 1994-2001 | CU Boulder | |
| (Crystallographic and thermodynamic studies of ssDNA sequence discrimination with the Oxytricha nova telomere end -binding protein.) | ||||
| Deborah S. Wuttke | post-doc | 2001-2006 | CU Boulder (Chemistry Tree) | |
| Christopher Miller | post-doc | 2006-2007 | Brandeis (Chemistry Tree) | |
Children
Sign in to add trainee| Nathaniel Lazar | research assistant | 2008-2010 | Brandeis |
| Marcus R. Kelly | research assistant | 2009-2011 | Brandeis |
| Adam M. Drake | research assistant | 2010-2013 | Brandeis |
| Joseph R. Jacobowitz | research assistant | 2012-2014 | Brandeis (Telomere and Telomerase Tree) |
| Michelle Yen Fry | research assistant | 2013-2014 | Brandeis |
| Changhan Xu | research assistant | 2015-2017 | Brandeis |
| Miriam Hood | research assistant | 2015-2018 | Brandeis |
| Simon Olsson | grad student | 2012-2012 | Brandeis |
| Jeffrey I. Boucher | grad student | 2008-2013 | Brandeis |
| Phillip A. Steindel | grad student | 2008-2014 | Brandeis (Telomere and Telomerase Tree) |
| Kristine Ann Mackin | grad student | 2010-2014 | Brandeis (Telomere and Telomerase Tree) |
| Erin Devine | grad student | 2011-2015 | Brandeis |
| Richard A. Roy | grad student | 2012-2018 | Brandeis |
| Brian Clifford Beckett | grad student | 2013-2019 | Brandeis |
| Jacob D. Wirth | grad student | 2014-2019 | Brandeis |
| Christoffer H. Norn | grad student | 2016-2019 | University of Lund |
| Michael Sennett | grad student | 2018-2022 | Brandeis |
Collaborators
Sign in to add collaborator| Christopher Miller | collaborator | 2007- | Brandeis (Chemistry Tree) |
| Paul A. Garrity | collaborator | 2009- | Brandeis (Neurotree) |
| Jeff Gelles | collaborator | 2010- | Brandeis (Chemistry Tree) |
| Nikolaus Grigorieff | collaborator | 2011- | Brandeis |
| Thomas Hamelryck | collaborator | 2011- | Copenhagen University (Computational Biology Tree) |
| Kantilal Vardichand Mardia | collaborator | 2011- | University of Leeds |
| Dorothee Kern | collaborator | 2012- | Brandeis (Telomere and Telomerase Tree) |
| Daniel D. Oprian | collaborator | 2012- | Brandeis (Neurotree) |
BETA: Related publications
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Publications
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| Frank HM, Walujkar S, Walsh RM, et al. (2024) Structural basis of ligand specificity and channel activation in an insect gustatory receptor. Cell Reports. 43: 114035 |
| Frank HM, Walujkar S, Walsh RM, et al. (2023) Structure of an insect gustatory receptor. Biorxiv : the Preprint Server For Biology |
| Ordabayev YA, Friedman LJ, Gelles J, et al. (2022) Bayesian machine learning analysis of single-molecule fluorescence colocalization images. Elife. 11 |
| Stiller JB, Otten R, Häussinger D, et al. (2022) Structure determination of high-energy states in a dynamic protein ensemble. Nature. 603: 528-535 |
| Norn C, André I, Theobald DL. (2021) A thermodynamic model of protein structure evolution explains empirical amino acid substitution matrices. Protein Science : a Publication of the Protein Society |
| Moreta LS, Al-Sibahi AS, Theobald D, et al. (2019) A Probabilistic Programming Approach to Protein Structure Superposition. Proceedings of the ... Ieee Symposium On Computational Intelligence in Bioinformatics and Computational Biology : Cibcb. Ieee Symposium On Computational Intelligence in Bioinformatics and Computational Biology. 2019 |
| Wirth JD, Boucher JI, Jacobowitz JR, et al. (2018) Functional and Structural Resilience of the Active Site Loop in the Evolution of Plasmodium Lactate Dehydrogenase. Biochemistry |
| Lamarche LB, Kumar RP, Trieu MM, et al. (2017) Purification and Characterization of RhoPDE, a Retinylidene/Phosphodiesterase Fusion Protein and Potential Optogenetics Tool from the Choanoflagellate Salpingoeca rosetta. Biochemistry |
| Trieu MM, Devine EL, Lamarche LB, et al. (2017) Expression, Purification, and Spectral Tuning of RhoGC, a Retinylidene/Guanylyl Cyclase Fusion Protein and Optogenetics Tool from the Aquatic Fungus Blastocladiella emersonii. The Journal of Biological Chemistry |
| Nguyen V, Wilson C, Hoemberger M, et al. (2016) Evolutionary drivers of thermoadaptation in enzyme catalysis. Science (New York, N.Y.) |