Harsh B. Pathak, Ph.D.
Affiliations: | 2006 | Pennsylvania State University, State College, PA, United States |
Area:
Microbiology Biology, Molecular Biology, Virology BiologyGoogle:
"Harsh Pathak"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Craig Eugene Cameron | grad student | 2006 | Penn State | |
| (Towards a unified model for initiation of the first step of picornavirus genome replication.) | ||||
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Publications
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| Oh HS, Pathak HB, Goodfellow IG, et al. (2009) Insight into poliovirus genome replication and encapsidation obtained from studies of 3B-3C cleavage site mutants. Journal of Virology. 83: 9370-87 |
| Pathak HB, Oh HS, Goodfellow IG, et al. (2008) Picornavirus genome replication: roles of precursor proteins and rate-limiting steps in oriI-dependent VPg uridylylation. The Journal of Biological Chemistry. 283: 30677-88 |
| Shen M, Reitman ZJ, Zhao Y, et al. (2008) Picornavirus genome replication. Identification of the surface of the poliovirus (PV) 3C dimer that interacts with PV 3Dpol during VPg uridylylation and construction of a structural model for the PV 3C2-3Dpol complex. The Journal of Biological Chemistry. 283: 875-88 |
| Shen M, Wang Q, Yang Y, et al. (2007) Human rhinovirus type 14 gain-of-function mutants for oriI utilization define residues of 3C(D) and 3Dpol that contribute to assembly and stability of the picornavirus VPg uridylylation complex. Journal of Virology. 81: 12485-95 |
| Pathak HB, Arnold JJ, Wiegand PN, et al. (2007) Picornavirus genome replication: assembly and organization of the VPg uridylylation ribonucleoprotein (initiation) complex. The Journal of Biological Chemistry. 282: 16202-13 |
| Marcotte LL, Wass AB, Gohara DW, et al. (2007) Crystal structure of poliovirus 3CD protein: virally encoded protease and precursor to the RNA-dependent RNA polymerase. Journal of Virology. 81: 3583-96 |
| Franco D, Pathak HB, Cameron CE, et al. (2005) Stimulation of poliovirus RNA synthesis and virus maturation in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDpro. Virology Journal. 2: 86 |
| Franco D, Pathak HB, Cameron CE, et al. (2005) Stimulation of poliovirus synthesis in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDpro. Journal of Virology. 79: 6358-67 |
| Pathak HB, Ghosh SK, Roberts AW, et al. (2002) Structure-function relationships of the RNA-dependent RNA polymerase from poliovirus (3Dpol). A surface of the primary oligomerization domain functions in capsid precursor processing and VPg uridylylation. The Journal of Biological Chemistry. 277: 31551-62 |
| Wei L, Huhn JS, Mory A, et al. (2001) Proteinase-polymerase precursor as the active form of feline calicivirus RNA-dependent RNA polymerase. Journal of Virology. 75: 1211-9 |