Robert M. Rutledge, Ph.D.
Affiliations: | 2006 | The Catholic University of America, Washington, DC |
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Sign in to add mentorJohn E. Golin | grad student | 2006 | Catholic University | |
(Vps3p dependent multidrug resistance in Saccharomyces cerevisiae.) |
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Publications
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Rutledge RM, Esser L, Ma J, et al. (2011) Toward understanding the mechanism of action of the yeast multidrug resistance transporter Pdr5p: a molecular modeling study. Journal of Structural Biology. 173: 333-44 |
Ananthaswamy N, Rutledge R, Sauna ZE, et al. (2010) The signaling interface of the yeast multidrug transporter Pdr5 adopts a cis conformation, and there are functional overlap and equivalence of the deviant and canonical Q-loop residues. Biochemistry. 49: 4440-9 |
Sauna ZE, Bohn SS, Rutledge R, et al. (2008) Mutations define cross-talk between the N-terminal nucleotide-binding domain and transmembrane helix-2 of the yeast multidrug transporter Pdr5: possible conservation of a signaling interface for coupling ATP hydrolysis to drug transport. The Journal of Biological Chemistry. 283: 35010-22 |
Rutledge RM, Ghislain M, Mullins JM, et al. (2008) Pdr5-mediated multidrug resistance requires the CPY-vacuolar sorting protein Vps3: are xenobiotic compounds routed from the vacuole to plasma membrane transporters for efflux? Molecular Genetics and Genomics : Mgg. 279: 573-83 |