Brad T. Benedetti, Ph.D.

Affiliations: 
2011 Chemistry Virginia Commonwealth University, Richmond, VA, United States 
Area:
General Chemistry, Biochemistry, Pharmaceutical Chemistry
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Nicholas P. Farrell grad student 2011 VCU
 (Drug Design, Biological Activity, and Metabolic Consequences of Cytotoxic Platinum Compounds: Utilizing Fluorescent Tagging to Understand Drug Action and Metabolism.)
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Publications

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Benedetti BT, Quintal S, Farrell NP. (2011) Modulation of drug activation profiles through carboxylate ligand modification in cytotoxic trans-platinum planar amine compounds. Dalton Transactions (Cambridge, England : 2003). 40: 10983-8
Benedetti BT, Peterson EJ, Kabolizadeh P, et al. (2011) Effects of noncovalent platinum drug-protein interactions on drug efficacy: use of fluorescent conjugates as probes for drug metabolism. Molecular Pharmaceutics. 8: 940-8
Peterson E, Silva H, Menon V, et al. (2011) Abstract C171: TriplatinNC, a nucleolar-targeting platinum agent. Heparan sulfate-mediated cell entry, localization, and apoptosis. Molecular Cancer Therapeutics. 10
Montero EI, Benedetti BT, Mangrum JB, et al. (2007) Pre-association of polynuclear platinum anticancer agents on a protein, human serum albumin. Implications for drug design. Dalton Transactions (Cambridge, England : 2003). 4938-42
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