Soren Ottosen, Ph.D.

2003 Michigan State University, East Lansing, MI 
Molecular Biology, Microbiology Biology, Biochemistry
"Soren Ottosen"
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Steven J. Triezenberg grad student 2003 Michigan State
 (Phosphorylation of the transcriptional activator VP16 during lytic infection by herpes simplex type 1.)
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van der Ree MH, van der Meer AJ, van Nuenen AC, et al. (2016) Miravirsen dosing in chronic hepatitis C patients results in decreased microRNA-122 levels without affecting other microRNAs in plasma. Alimentary Pharmacology & Therapeutics. 43: 102-13
Ottosen S, Parsley TB, Yang L, et al. (2015) In vitro antiviral activity and preclinical and clinical resistance profile of miravirsen, a novel anti-hepatitis C virus therapeutic targeting the human factor miR-122. Antimicrobial Agents and Chemotherapy. 59: 599-608
Hagedorn PH, Yakimov V, Ottosen S, et al. (2013) Hepatotoxic potential of therapeutic oligonucleotides can be predicted from their sequence and modification pattern. Nucleic Acid Therapeutics. 23: 302-10
Ilginis T, Ottosen S, Harbo Bundsgaard K, et al. (2012) Polypoidal choroidal vasculopathy in patients diagnosed with neovascular age-related macular degeneration in Denmark. Acta Ophthalmologica. 90: e487-8
Misaghi S, Ottosen S, Izrael-Tomasevic A, et al. (2009) Association of C-terminal ubiquitin hydrolase BRCA1-associated protein 1 with cell cycle regulator host cell factor 1. Molecular and Cellular Biology. 29: 2181-92
Savas JN, Makusky A, Ottosen S, et al. (2008) Huntington's disease protein contributes to RNA-mediated gene silencing through association with Argonaute and P bodies. Proceedings of the National Academy of Sciences of the United States of America. 105: 10820-5
Ottosen S, Herrera FJ, Doroghazi JR, et al. (2006) Phosphorylation of the VP16 transcriptional activator protein during herpes simplex virus infection and mutational analysis of putative phosphorylation sites. Virology. 345: 468-81
Ottosen S, Herrera FJ, Triezenberg SJ. (2002) Transcription. Proteasome parts at gene promoters. Science (New York, N.Y.). 296: 479-81
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