Denise L. Holzle, Ph.D.
Affiliations: | 2010 | University of Illinois at Chicago, Health Sciences Center, Chicago, IL 60612, United States |
Area:
Molecular Biology, Biochemistry, Cell BiologyGoogle:
"Denise Holzle"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Sylvie Blond | grad student | 2010 | University of Illinois at Chicago, Health Sciences Center | |
| (Novel chemical GSK3beta and HDAC inhibitors: Evaluation of antiproliferative and protective effects.) | ||||
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Publications
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| Neelarapu R, Holzle DL, Velaparthi S, et al. (2011) Design, synthesis, docking, and biological evaluation of novel diazide-containing isoxazole- and pyrazole-based histone deacetylase probes. Journal of Medicinal Chemistry. 54: 4350-64 |
| He B, Velaparthi S, Pieffet G, et al. (2009) Binding ensemble profiling with photoaffinity labeling (BEProFL) approach: mapping the binding poses of HDAC8 inhibitors. Journal of Medicinal Chemistry. 52: 7003-13 |
| Kim KH, Gaisina I, Gallier F, et al. (2009) Use of molecular modeling, docking, and 3D-QSAR studies for the determination of the binding mode of benzofuran-3-yl-(indol-3-yl) maleimides as GSK-3β inhibitors Journal of Molecular Modeling. 15: 1463-1479 |
| Gaisina IN, Gallier F, Ougolkov AV, et al. (2009) From a natural product lead to the identification of potent and selective benzofuran-3-yl-(indol-3-yl)maleimides as glycogen synthase kinase 3βinhibitors that suppress proliferation and survival of pancreatic cancer cells Journal of Medicinal Chemistry. 52: 1853-1863 |