Michael Thomenius, Ph.D.

Affiliations: 
2004 Case Western Reserve University, Cleveland Heights, OH, United States 
Area:
Cell Biology, Biochemistry
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"Michael Thomenius"
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Clark W. Distelhorst grad student 2004 Case Western
 (B-cell lymphoma-2 protein family, apoptosis and the endoplasmic reticulum.)
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Publications

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Mitchell LH, Boriack-Sjodin PA, Smith S, et al. (2016) Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor Acs Medicinal Chemistry Letters. 7: 134-138
Yang CS, Sinenko SA, Thomenius MJ, et al. (2014) The deubiquitinating enzyme DUBAI stabilizes DIAP1 to suppress Drosophila apoptosis. Cell Death and Differentiation. 21: 604-11
Thomenius M, Freel CD, Horn S, et al. (2011) Mitochondrial fusion is regulated by Reaper to modulate Drosophila programmed cell death Cell Death and Differentiation. 18: 1640-1650
Horn SR, Thomenius MJ, Johnson ES, et al. (2011) Regulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stability. Molecular Biology of the Cell. 22: 1207-16
Yang CS, Thomenius MJ, Gan EC, et al. (2010) Metabolic regulation of Drosophila apoptosis through inhibitory phosphorylation of Dronc. The Embo Journal. 29: 3196-207
Freel CD, Richardson DA, Thomenius MJ, et al. (2008) Mitochondrial localization of Reaper to promote inhibitors of apoptosis protein degradation conferred by GH3 domain-lipid interactions. The Journal of Biological Chemistry. 283: 367-79
Margolis SS, Perry JA, Forester CM, et al. (2006) Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis. Cell. 127: 759-73
Thomenius M, Kornbluth S. (2006) Multifunctional reaper: Sixty-five amino acids of fury Cell Death and Differentiation. 13: 1305-1309
Thomenius MJ, Distelhorst CW. (2003) Bcl-2 on the endoplasmic reticulum: protecting the mitochondria from a distance. Journal of Cell Science. 116: 4493-9
Wang Z, Malone MH, Thomenius MJ, et al. (2003) Dexamethasone-induced gene 2 (dig2) is a novel pro-survival stress gene induced rapidly by diverse apoptotic signals. The Journal of Biological Chemistry. 278: 27053-8
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