David A. Brott, Ph.D.
Affiliations: | 2006 | University of Michigan, Ann Arbor, Ann Arbor, MI |
Area:
Toxicology, PathologyGoogle:
"David Brott"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Rudy J. Richardson | grad student | 2006 | University of Michigan | |
| (Mechanistic studies and potential diagnostic markers of drug -induced vascular injury.) | ||||
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Publications
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| Ebrahimi A, Raichlen JS, Pointon A, et al. (2020) Drug-induced myocardial dysfunction - recommendations for assessment in clinical and pre-clinical studies. Expert Opinion On Drug Safety. 1-14 |
| Roth SE, Avigan MI, Bourdet D, et al. (2019) Next Generation DILI Biomarkers: Prioritization of Biomarkers for Qualification and Best Practices for Biospecimen Collection in Drug Development. Clinical Pharmacology and Therapeutics |
| Brott DA, Goodman MJ, Hermann RP, et al. (2018) Are laboratory parameter (biomarker) values similar to the healthy volunteer reference range in all patient populations? Drug Design, Development and Therapy. 12: 2757-2773 |
| Brott DA, Furlong ST, Adler SH, et al. (2015) Characterization of renal biomarkers for use in clinical trials: effect of preanalytical processing and qualification using samples from subjects with diabetes. Drug Design, Development and Therapy. 9: 3191-8 |
| Bendjama K, Guionaud S, Aras G, et al. (2014) Translation strategy for the qualification of drug-induced vascular injury biomarkers. Toxicologic Pathology. 42: 658-71 |
| Brott DA, Adler SH, Arani R, et al. (2014) Characterization of renal biomarkers for use in clinical trials: biomarker evaluation in healthy volunteers. Drug Design, Development and Therapy. 8: 227-37 |
| Brott DA, Katein A, Thomas H, et al. (2014) Evaluation of von Willebrand factor and von Willebrand factor propeptide in models of vascular endothelial cell activation, perturbation, and/or injury. Toxicologic Pathology. 42: 672-83 |
| Brott DA, Bentley P, Nadella MV, et al. (2013) Renal biomarker changes associated with hyaline droplet nephropathy in rats are time and potentially compound dependent. Toxicology. 303: 133-8 |
| Brott DA, Richardson RJ, Louden CS. (2012) Evidence for the nitric oxide pathway as a potential mode of action in fenoldopam-induced vascular injury. Toxicologic Pathology. 40: 874-86 |
| Desai K, Brott D, Hu X, et al. (2012) A systems biology approach for detecting toxicity-related hotspots inside protein interaction networks. Journal of Bioinformatics and Computational Biology. 9: 647-62 |