Xiongwen Chen, Ph.D.

Affiliations: 
2003 Temple University, Philadelphia, PA, United States 
Area:
Pathology, Medical Biophysics, Biomedical Engineering
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"Xiongwen Chen"
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Steven R. Houser grad student 2003 Temple University
 (L-type calcium channel biophysical properties, density and regulation are altered in failing human ventricular myocytes and recover after support with mechanical assist devices.)
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Publications

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Bai Y, Zhang X, Li Y, et al. (2024) Protein Kinase A Is a Master Regulator of Physiological and Pathological Cardiac Hypertrophy. Circulation Research
Li Y, Johnson JP, Yang Y, et al. (2023) The Effects of Maternal Hypothyroidism on Postnatal Cardiomyocyte Proliferation and Cardiac Disease Responses of the Progeny. American Journal of Physiology. Heart and Circulatory Physiology
Li Y, Kubo H, Yu D, et al. (2023) Combining Three Independent Pathological Stressors Induces a Heart Failure with Preserved Ejection Fraction Phenotype. American Journal of Physiology. Heart and Circulatory Physiology
Gross P, Johnson J, Romero CM, et al. (2020) Interaction of the Joining Region in Junctophilin-2 with the L-type Ca Channel Is Pivotal for Cardiac Dyad Assembly and Intracellular Ca Dynamics. Circulation Research
Zhang X, Li Y, Zhang X, et al. (2020) A low voltage activated Ca current found in a subset of human ventricular myocytes. Channels (Austin, Tex.). 14: 231-245
Zhang Y, Zhang X, Li Y, et al. (2020) Cardiomyocyte PKA ablation eliminates cardiac β-adrenergic response without adverse effects on the heart Journal of Molecular and Cellular Cardiology. 140: 25-26
Chen X, Zhang X, Gross S, et al. (2019) Acetylation of SERCA2a, Another Target for Heart Failure Treatment? Circulation Research. 124: 1285-1287
Zhang Y, Wang WE, Zhang X, et al. (2019) Cardiomyocyte PKA Ablation Enhances Basal Contractility While Eliminates Cardiac β-Adrenergic Response Without Adverse Effects on the Heart. Circulation Research
Yang J, Zhang X, Ao S, et al. (2019) Abstract 360: PKA is Needed for Acute Adaptation for Cardiac Stress Circulation Research. 125
Jiang J, Lan C, Li L, et al. (2018) A novel porcupine inhibitor blocks WNT pathways and attenuates cardiac hypertrophy. Biochimica Et Biophysica Acta
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