Geoffrey D. Mills, Ph.D.

Affiliations: 
2006 Temple University, Philadelphia, PA, United States 
Area:
Animal Physiology Biology
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Steven R. Houser grad student 2006 Temple University
 (Contractile reserve in pressure -overload hypertrophy and heart failure.)
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Publications

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Mills GD, Harris DM, Chen X, et al. (2007) Intracellular sodium determines frequency-dependent alterations in contractility in hypertrophied feline ventricular myocytes. American Journal of Physiology. Heart and Circulatory Physiology. 292: H1129-38
Mills GD, Kubo H, Harris DM, et al. (2006) Phosphorylation of phospholamban at threonine-17 reduces cardiac adrenergic contractile responsiveness in chronic pressure overload-induced hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 291: H61-70
Chen X, Zhang X, Kubo H, et al. (2005) Ca2+ influx-induced sarcoplasmic reticulum Ca2+ overload causes mitochondrial-dependent apoptosis in ventricular myocytes. Circulation Research. 97: 1009-17
Harris DM, Mills GD, Chen X, et al. (2005) Alterations in early action potential repolarization causes localized failure of sarcoplasmic reticulum Ca2+ release. Circulation Research. 96: 543-50
Jung AS, Quaile MP, Mills GD, et al. (2005) Pharmacological effects of ATI22-107 [2-(2-{2-[2-chloro-4-(6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)-phenoxy]-acetylamino}-ethoxymethyl)-4-(2-chloro-phenyl)-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester)], a novel dual pharmacophore, on myocyte calcium cycling and contractility. The Journal of Pharmacology and Experimental Therapeutics. 312: 517-24
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