Kimon C. Kanelakis, Ph.D.
Affiliations: | 2002 | University of Michigan, Ann Arbor, Ann Arbor, MI |
Area:
Pharmacology, Molecular BiologyGoogle:
"Kimon Kanelakis"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| William B. Pratt | grad student | 2002 | University of Michigan | |
| (Nucelotide binding states of hsp70 and hsp90 during assembly of heterocomplexes between the glucocorticoid receptor and hsp90.) | ||||
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Publications
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| Lim WK, Kanelakis KC, Neubig RR. (2013) Regulation of G protein signaling by the 70kDa heat shock protein. Cellular Signalling. 25: 389-96 |
| Galigniana MD, Piwien Pilipuk G, Kanelakis KC, et al. (2004) Molecular mechanism of activation and nuclear translocation of the mineralocorticoid receptor upon binding of pregnanesteroids. Molecular and Cellular Endocrinology. 217: 167-79 |
| Kanelakis KC, Pratt WB. (2003) Regulation of glucocorticoid receptor ligand-binding activity by the hsp90/hsp70-based chaperone machinery. Methods in Enzymology. 364: 159-73 |
| Morishima Y, Kanelakis KC, Murphy PJ, et al. (2003) The hsp90 cochaperone p23 is the limiting component of the multiprotein hsp90/hsp70-based chaperone system in vivo where it acts to stabilize the client protein: hsp90 complex. The Journal of Biological Chemistry. 278: 48754-63 |
| Zhang Z, Quick MK, Kanelakis KC, et al. (2003) Characterization of a plant homolog of hop, a cochaperone of hsp90. Plant Physiology. 131: 525-35 |
| Krishna P, Kanelakis KC. (2003) The 70-kDa protein bound to hsp90 in wheat germ lysate is a plant homologue of animal Hop Physiologia Plantarum. 119: 456-462 |
| Piwien-Pilipuk G, Kanelakis KC, Galigniana MD. (2002) Correlation between pregnanesteroid conformation, receptor affinity, and anti-natriuretic effect. European Journal of Pharmacology. 454: 131-43 |
| Kanelakis KC, Shewach DS, Pratt WB. (2002) Nucleotide binding states of hsp70 and hsp90 during sequential steps in the process of glucocorticoid receptor.hsp90 heterocomplex assembly. The Journal of Biological Chemistry. 277: 33698-703 |
| Billecke SS, Bender AT, Kanelakis KC, et al. (2002) hsp90 is required for heme binding and activation of apo-neuronal nitric-oxide synthase: geldanamycin-mediated oxidant generation is unrelated to any action of hsp90. The Journal of Biological Chemistry. 277: 20504-9 |
| Piwien-Pilipuk G, Kanelakis KC, Ghini AA, et al. (2002) Modification of an essential amino group in the mineralocorticoid receptor evidences a differential conformational change of the receptor protein upon binding of antagonists, natural agonists and the synthetic agonist 11,19-oxidoprogesterone. Biochimica Et Biophysica Acta. 1589: 31-48 |