Abigail R. Lambert, Ph.D.
Affiliations: | 2009 | University of Washington, Seattle, Seattle, WA |
Area:
BiochemistryGoogle:
"Abigail Lambert"Mean distance: (not calculated yet)
Parents
Sign in to add mentorBarry L. Stoddard | grad student | 2009 | University of Washington | |
(Structure determination, thermodynamic characterization, and computational redesign of the rare-cutting restriction endonuclease NotI.) |
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Publications
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Luyten YA, Hausman DE, Young JC, et al. (2022) Identification and characterization of the WYL BrxR protein and its gene as separable regulatory elements of a BREX phage restriction system. Nucleic Acids Research |
Lambert AR, Hallinan JP, Werther R, et al. (2020) Optimization of Protein Thermostability and Exploitation of Recognition Behavior to Engineer Altered Protein-DNA Recognition. Structure (London, England : 1993) |
Niyonzima N, Lambert AR, Werther R, et al. (2017) Tuning DNA binding affinity and cleavage specificity of an engineered gene-targeting nuclease via surface display, flow cytometry and cellular analyses. Protein Engineering, Design & Selection : Peds. 30: 503-522 |
Moffett HF, Coon ME, Radtke S, et al. (2017) Hit-and-run programming of therapeutic cytoreagents using mRNA nanocarriers. Nature Communications. 8: 389 |
Werther R, Hallinan JP, Lambert AR, et al. (2017) Crystallographic analyses illustrate significant plasticity and efficient recoding of meganuclease target specificity. Nucleic Acids Research |
Jacoby K, Lambert AR, Scharenberg AM. (2017) Characterization of homing endonuclease binding and cleavage specificities using yeast surface display SELEX (YSD-SELEX). Nucleic Acids Research. 45: e11 |
Jacoby K, Lambert AR, Scharenberg AM. (2016) Characterization of homing endonuclease binding and cleavage specificities using yeast surface display SELEX (YSD-SELEX). Nucleic Acids Research |
Lambert AR, Hallinan JP, Shen BW, et al. (2016) Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity. Structure (London, England : 1993) |
Shen BW, Lambert A, Walker BC, et al. (2015) The structural basis of asymmetry in DNA binding and cleavage as exhibited by the I-SmaMI LAGLIDADG meganuclease. Journal of Molecular Biology |
Shen BW, Walker B, Lambert A, et al. (2015) The structural basis of asymmetry in DNA recognition and catalysis: binding and cleavage by the I-SmaMI meganuclease Acta Crystallographica Section a Foundations and Advances. 71: s251-s251 |