Brian C. Beard, Ph.D.
Affiliations: | 2003 | Washington State University, Pullman, WA, United States |
Area:
Biochemistry, Molecular BiologyGoogle:
"Brian Beard"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Michael J. Smerdon | grad student | 2003 | WSU | |
| (Base excision repair of dynamic chromatin substrates.) | ||||
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Publications
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| Navarro S, Quintana-Bustamante O, Sanchez-Dominguez R, et al. (2021) Preclinical studies of efficacy thresholds and tolerability of a clinically ready lentiviral vector for pyruvate kinase deficiency treatment. Molecular Therapy. Methods & Clinical Development. 22: 350-359 |
| Czechowicz A, Rio P, Bueren JE, et al. (2020) Changing the Natural History of Fanconi Anemia Complementation Group-À with Gene Therapy: Early Results of U.S. Phase I Study of Lentiviral-Mediated Ex-Vivo FANCA Gene Insertion in Human Stem and Progenitor Cells Biology of Blood and Marrow Transplantation. 26 |
| Czechowicz A, Roncarolo MG, Beard BC, et al. (2019) Changing the Natural History of Fanconi Anemia Complementation Group-A with Gene Therapy: Early Results of U.S. Phase I Study of Lentiviral-Mediated Ex-VivoFANCA Gene Insertion in Human Stem and Progenitor Cells Blood. 134: 3350-3350 |
| Almarza E, Mesa-Núñez C, Damián C, et al. (2019) Gene Therapy for Lad-I Immunodeficiency: Preclinical Evaluation of HSC Transduction Under Optimized GMP-Conditions Blood. 134: 5751-5751 |
| Haworth KG, Ironside C, Ramirez MA, et al. (2018) Minimal conditioning in Fanconi anemia promotes multi-lineage marrow engraftment at ten-fold lower cell doses. The Journal of Gene Medicine. e3050 |
| Ruan H, Qiu S, Beard BC, et al. (2016) Creation of zebularine-resistant human cytidine deaminase mutants to enhance the chemoprotection of hematopoietic stem cells. Protein Engineering, Design & Selection : Peds |
| Burtner CR, Chandrasekaran D, Santos EB, et al. (2015) (211)Astatine-Conjugated Monoclonal CD45 Antibody-Based Nonmyeloablative Conditioning for Stem Cell Gene Therapy. Human Gene Therapy. 26: 399-406 |
| Kiem HP, Arumugam PI, Burtner CR, et al. (2014) Pigtailed macaques as a model to study long-term safety of lentivirus vector-mediated gene therapy for hemoglobinopathies. Molecular Therapy. Methods & Clinical Development. 1: 14055 |
| Adair JE, Johnston SK, Mrugala MM, et al. (2014) Gene therapy enhances chemotherapy tolerance and efficacy in glioblastoma patients. The Journal of Clinical Investigation. 124: 4082-92 |
| Beard BC, Adair JE, Trobridge GD, et al. (2014) High-throughput genomic mapping of vector integration sites in gene therapy studies. Methods in Molecular Biology (Clifton, N.J.). 1185: 321-44 |