Sandra B. Gabelli, Ph.D.

Affiliations: 
1983-1988 Dept. Mathematics Universidad Nacional del Sur (Argentina) 
 1993- Medicine, Oncology, Biophysics and Biophysical Chemistry Johns Hopkins University School of Medicine, Baltimore, MD, United States 
Area:
PI3K, Nudix, Sodium Voltage Gated Channels, FPPS, Immunotherapy, structural biology
Website:
https://gabelli.med.jhmi.edu/
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"Sandra B. Gabelli"
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Parents

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L Mario Amzel grad student 2000 Johns Hopkins
 (The structure of the ADP -ribose pyrophosphatase reveals the versatility of the Nudix hydrolases.)
Bert Vogelstein post-doc Johns Hopkins Medical School/HHMI
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Publications

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Nathan S, Gabelli SB, Yoder JB, et al. (2021) Structural basis of cytoplasmic NaV1.5 and NaV1.4 regulation. The Journal of General Physiology. 153
Maheshwari S, Kim YS, Aripirala S, et al. (2020) Identifying structural determinants of product specificity in Leishmania major farnesyl diphosphate synthase. Biochemistry
Chang TH, Hsieh FL, Smallwood PM, et al. (2020) Structure of the RECK CC domain, an evolutionary anomaly. Proceedings of the National Academy of Sciences of the United States of America
Branco Santos JC, de Melo JA, Maheshwari S, et al. (2020) Bisphosphonate-Based Molecules as Potential New Antiparasitic Drugs. Molecules (Basel, Switzerland). 25
Chakrabarti M, Gabelli SB, Amzel LM. (2020) Allosteric Activation of PI3Kα Results in Dynamic Access to Catalytically Competent Conformations. Structure (London, England : 1993)
Miller MS, Douglass J, Hwang MS, et al. (2019) An engineered antibody fragment targeting mutant β-catenin via Major Histocompatibility Complex I neoantigen presentation. The Journal of Biological Chemistry
Thirawatananond P, McPherson RL, Malhi J, et al. (2019) Structural analyses of NudT16-ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins. Scientific Reports. 9: 5940
Yoder JB, Ben-Johny M, Farinelli F, et al. (2019) Ca-dependent regulation of sodium channels Na1.4 and Na1.5 is controlled by the post-IQ motif. Nature Communications. 10: 1514
Miller MS, Thompson PE, Gabelli SB. (2019) Structural Determinants of Isoform Selectivity in PI3K Inhibitors. Biomolecules. 9
Miller MS, Maheshwari S, Shi W, et al. (2019) Getting the Most Out of Your Crystals: Data Collection at the New High-Flux, Microfocus MX Beamlines at NSLS-II. Molecules (Basel, Switzerland). 24
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