Sandra B. Gabelli, Ph.D.
Affiliations: | Medicine, Oncology, Biophysics and Biophysical Chemistry | Johns Hopkins University School of Medicine, Baltimore, MD, United States |
Area:
PI3K, Nudix, Sodium Voltage Gated Channels, FPPS, structural biologyGoogle:
"Sandra B. Gabelli"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| L Mario Amzel | grad student | 2000 | Johns Hopkins | |
| (The structure of the ADP -ribose pyrophosphatase reveals the versatility of the Nudix hydrolases.) | ||||
| Bert Vogelstein | post-doc | Johns Hopkins Medical School/HHMI | ||
Children
Sign in to add trainee| Mario A. Pizarro | research assistant | University of Maryland | |
| Puchong Thirawatananond | research assistant | 2014- | Johns Hopkins Medical School |
| Srinivas Aripirala | grad student | Johns Hopkins Medical School | |
| Krisna C. Duong-Ly | grad student | Johns Hopkins Medical School | |
| William Hong | grad student | Johns Hopkins Medical School | |
| Akunna Iheanacho | grad student | Johns Hopkins Medical School | |
| Diana Mandelker | grad student | 2010 | Johns Hopkins Medical School |
| Sweta Maheshwari | post-doc | Johns Hopkins Medical School | |
| Michelle Miller | post-doc | 2013- | Johns Hopkins Medical School |
Collaborators
Sign in to add collaborator| Maurice J. Bessman | collaborator | Johns Hopkins (Physics Tree) | |
| Roberto Docampo | collaborator | University of Georgia | |
| Suzanne O'Handley | collaborator | Rochester | |
| Eric Oldfield | collaborator | UIUC | |
| Bert Vogelstein | collaborator | Johns Hopkins Medical School/HHMI | |
| Gordon F. Tomaselli | collaborator | 2007- | Johns Hopkins Medical School/HHMI |
| Philip A. Cole | collaborator | 2012- | Johns Hopkins Medical School/HHMI |
BETA: Related publications
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Publications
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| Chakrabarti M, Gabelli SB, Amzel LM. (2020) Allosteric Activation of PI3Kα Results in Dynamic Access to Catalytically Competent Conformations. Structure (London, England : 1993) |
| Miller MS, Douglass J, Hwang MS, et al. (2019) An engineered antibody fragment targeting mutant β-catenin via Major Histocompatibility Complex I neoantigen presentation. The Journal of Biological Chemistry |
| Thirawatananond P, McPherson RL, Malhi J, et al. (2019) Structural analyses of NudT16-ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins. Scientific Reports. 9: 5940 |
| Yoder JB, Ben-Johny M, Farinelli F, et al. (2019) Ca-dependent regulation of sodium channels Na1.4 and Na1.5 is controlled by the post-IQ motif. Nature Communications. 10: 1514 |
| Miller MS, Thompson PE, Gabelli SB. (2019) Structural Determinants of Isoform Selectivity in PI3K Inhibitors. Biomolecules. 9 |
| Miller MS, Maheshwari S, Shi W, et al. (2019) Getting the Most Out of Your Crystals: Data Collection at the New High-Flux, Microfocus MX Beamlines at NSLS-II. Molecules (Basel, Switzerland). 24 |
| Maheshwari S, Shimokawa C, Rudzka K, et al. (2018) Effects of copper occupancy on the conformational landscape of peptidylglycine α-hydroxylating monooxygenase. Communications Biology. 1: 74 |
| Chu N, Salguero AL, Liu AZ, et al. (2018) Akt Kinase Activation Mechanisms Revealed Using Protein Semisynthesis. Cell |
| Banerjee R, Yoder JB, Yue DT, et al. (2018) Bilobal architecture is a requirement for calmodulin signaling to Ca1.3 channels. Proceedings of the National Academy of Sciences of the United States of America |
| Shumar SA, Kerr EW, Geldenhuys WJ, et al. (2018) Nudt19 is a renal CoA diphosphohydrolase with biochemical and regulatory properties that are distinct from the hepatic Nudt7 isoform. The Journal of Biological Chemistry |