David L. Masica, Ph.D.

Affiliations: 
2009 Johns Hopkins University, Baltimore, MD 
Area:
General Biophysics
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Parents

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Jeffrey J. Gray grad student 2009 Johns Hopkins (Computational Biology Tree)
 (Structure determination and design of biomineral -associated proteins.)
Jan H. Hoh grad student 2009 Johns Hopkins
 (Structure determination and design of biomineral -associated proteins.)
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Publications

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Tokheim C, Bhattacharya R, Niknafs N, et al. (2016) Exome-scale discovery of hotspot mutation regions in human cancer using 3D protein structure. Cancer Research
Masica DL, Karchin R. (2016) Towards Increasing the Clinical Relevance of In Silico Methods to Predict Pathogenic Missense Variants. Plos Computational Biology. 12: e1004725
Douville C, Masica DL, Stenson PD, et al. (2015) Assessing the Pathogenicity of Insertion and Deletion Variants with the Variant Effect Scoring Tool (VEST-Indel). Human Mutation
Springer S, Wang Y, Molin MD, et al. (2015) A Combination of Molecular Markers and Clinical Features Improve the Classification of Pancreatic Cysts. Gastroenterology
Chung CH, Guthrie VB, Masica DL, et al. (2015) Genomic alterations in head and neck squamous cell carcinoma determined by cancer gene-targeted sequencing. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 26: 1216-23
Masica DL, Sosnay PR, Raraigh KS, et al. (2015) Missense variants in CFTR nucleotide-binding domains predict quantitative phenotypes associated with cystic fibrosis disease severity. Human Molecular Genetics. 24: 1908-17
Masica DL, Li S, Douville C, et al. (2015) Predicting survival in head and neck squamous cell carcinoma from TP53 mutation. Human Genetics. 134: 497-507
Sosnay PR, Siklosi KR, Van Goor F, et al. (2013) Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene. Nature Genetics. 45: 1160-7
Tarasevich BJ, Perez-Salas U, Masica DL, et al. (2013) Neutron reflectometry studies of the adsorbed structure of the amelogenin, LRAP. The Journal of Physical Chemistry. B. 117: 3098-109
Masica DL, Karchin R. (2013) Collections of simultaneously altered genes as biomarkers of cancer cell drug response. Cancer Research. 73: 1699-708
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