Tianxiang Han, Ph.D.

Affiliations: 
2013 Pharmaceutical Sciences University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pharmacy
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"Tianxiang Han"
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Dhiren R. Thakker grad student 2013 UNC Chapel Hill
 (Interplay between metformin and serotonin transport in the gastrointestinal tract: A novel mechanism for the intestinal absorption and adverse effects of metformin.)
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Publications

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Proctor WR, Ming X, Bourdet D, et al. (2016) Why Does the Intestine Lack Basolateral Efflux Transporters for Cationic Compounds? A Provocative Hypothesis. Journal of Pharmaceutical Sciences. 105: 484-96
Cai H, Zhang Y, Han TK, et al. (2015) Cation-selective transporters are critical to the ampk-mediated antiproliferative effects of metformin in human breast cancer cells. International Journal of Cancer. Journal International Du Cancer
Han TK, Proctor WR, Costales CL, et al. (2015) Four cation-selective transporters contribute to apical uptake and accumulation of metformin in Caco-2 cell monolayers. The Journal of Pharmacology and Experimental Therapeutics. 352: 519-28
Han TK, Everett RS, Proctor WR, et al. (2013) Organic cation transporter 1 (OCT1/mOct1) is localized in the apical membrane of Caco-2 cell monolayers and enterocytes. Molecular Pharmacology. 84: 182-9
Swift B, Nebot N, Lee JK, et al. (2013) Sorafenib hepatobiliary disposition: mechanisms of hepatic uptake and disposition of generated metabolites. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 1179-86
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