Shayne K. Morris, Ph.D.

Affiliations: 
2000 University of Utah, Salt Lake City, UT 
Area:
Biochemistry, Molecular Biology
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Parents

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Janet E. Lindsley grad student 2000 University of Utah
 (Probing the topoisomerase II mechanism using mutants and inhibitors.)
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Publications

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Morris SK, Baird CL, Lindsley JE. (2000) Steady-state and rapid kinetic analysis of topoisomerase II trapped as the closed-clamp intermediate by ICRF-193. The Journal of Biological Chemistry. 275: 2613-8
Baird CL, Harkins TT, Morris SK, et al. (1999) Topoisomerase II drives DNA transport by hydrolyzing one ATP. Proceedings of the National Academy of Sciences of the United States of America. 96: 13685-90
Morris SK, Lindsley JE. (1999) Yeast topoisomerase II is inhibited by etoposide after hydrolyzing the first ATP and before releasing the second ADP. The Journal of Biological Chemistry. 274: 30690-6
Morris SK, Harkins TT, Tennyson RB, et al. (1999) Kinetic and thermodynamic analysis of mutant type II DNA topoisomerases that cannot covalently cleave DNA. The Journal of Biological Chemistry. 274: 3446-52
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