Christina S. Alves, Ph.D.
Affiliations: | 2009 | Johns Hopkins University, Baltimore, MD |
Area:
Chemical Engineering, Biomedical Engineering, Cell BiologyGoogle:
"Christina Alves"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Konstantinos Konstantopoulos | grad student | 2009 | Johns Hopkins | |
| (Fibrin(ogen) is a CD44 ligand on colon carcinoma cells: Biochemical and biophysical characterization, growth factor involvement, and diagnostic applications.) | ||||
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Publications
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| Zhou Y, Raju R, Alves C, et al. (2018) Debottlenecking protein secretion and reducing protein aggregation in the cellular host. Current Opinion in Biotechnology. 53: 151-157 |
| Wright C, Alves C, Estes S, et al. (2017) Leveraging a CHO cell line toolkit to accelerate biotherapeutics into the clinic. Biotechnology Progress |
| Johari YB, Estes SD, Alves CS, et al. (2015) Integrated cell and process engineering for improved transient production of a "difficult-to-express" fusion protein by CHO cells. Biotechnology and Bioengineering. 112: 2527-42 |
| Alves CS, Gilbert A, Dalvi S, et al. (2015) Integration of cell line and process development to overcome the challenge of a difficult to express protein. Biotechnology Progress |
| Alves CS, Prajapati S. (2015) Optimizing Chinese hamster ovary cell line development via targeted control of N-glycosylation Pharmaceutical Bioprocessing. 3: 443-461 |
| Alves CS, Konstantopoulos K. (2012) PDGF suppresses the sulfation of CD44v and potentiates CD44v-mediated binding of colon carcinoma cells to fibrin under flow. Plos One. 7: e41472 |
| Raman PS, Alves CS, Wirtz D, et al. (2012) Distinct kinetic and molecular requirements govern CD44 binding to hyaluronan versus fibrin(ogen). Biophysical Journal. 103: 415-23 |
| Raman PS, Alves CS, Wirtz D, et al. (2011) Single-molecule binding of CD44 to fibrin versus P-selectin predicts their distinct shear-dependent interactions in cancer. Journal of Cell Science. 124: 1903-10 |
| Alves CS, Yakovlev S, Medved L, et al. (2009) Biomolecular characterization of CD44-fibrin(ogen) binding: distinct molecular requirements mediate binding of standard and variant isoforms of CD44 to immobilized fibrin(ogen). The Journal of Biological Chemistry. 284: 1177-89 |
| Ghosh M, Alves C, Tong Z, et al. (2008) Multifunctional surfaces with discrete functionalized regions for biological applications. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 8134-42 |