Neal Castagnoli

1987 University of California, San Francisco, San Francisco, CA 
 1987- Virginia Polytechnic Institute and State University, Blacksburg, VA, United States 
Organic Chemistry, Pharmaceutical Chemistry, Biochemistry
"Neal Castagnoli"
DOI: 10.1021/jo01027a029

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Henry Rapoport grad student 1964 UC Berkeley
 (Synthesis of pyrrole and polypyrrole systems.)


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Mark S. Cushman grad student 1969-1973 UCSF
Wolfgang Sadee post-doc 1970 UCSF (Neurotree)
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Bergström MA, Isin EM, Castagnoli N, et al. (2011) Bioactivation pathways of the cannabinoid receptor 1 antagonist rimonabant Drug Metabolism and Disposition. 39: 1823-1832
Pretorius A, Ogunrombi MO, Fourie H, et al. (2010) Interactions of 1-methyl-3-phenylpyrrolidine and 3-methyl-1-phenyl-3-azabicyclo[3.1.0]hexane with monoamine oxidase B. Bioorganic & Medicinal Chemistry. 18: 4111-8
Mali'n TJ, Weidolf L, Castagnoli N, et al. (2010) P450-catalyzed vs. electrochemical oxidation of haloperidol studied by ultra-performance liquid chromatography/electrospray ionization mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 24: 1231-40
Strydom B, Malan SF, Castagnoli N, et al. (2010) Inhibition of monoamine oxidase by 8-benzyloxycaffeine analogues Bioorganic and Medicinal Chemistry. 18: 1018-1028
Manley-King CI, Terre'Blanche G, Castagnoli N, et al. (2009) Inhibition of monoamine oxidase B by N-methyl-2-phenylmaleimides Bioorganic and Medicinal Chemistry. 17: 3104-3110
Pretorius A, Ogunrombi MO, Terre'blanche G, et al. (2008) Deuterium isotope effects for the oxidation of 1-methyl-3-phenyl-3-pyrrolinyl analogues by monoamine oxidase B. Bioorganic & Medicinal Chemistry. 16: 8813-7
Frédérick R, Dumont W, Ooms F, et al. (2006) Synthesis, structural reassignment, and biological activity of type B MAO inhibitors based on the 5H-indeno[1,2-c]pyridazin-5-one core. Journal of Medicinal Chemistry. 49: 3743-7
Jurva U, Bissel P, Isin EM, et al. (2005) Model electrochemical-mass spectrometric studies of the cytochrome P450-catalyzed oxidations of cyclic tertiary allylamines Journal of the American Chemical Society. 127: 12368-12377
Liu X, Zang L, Van der Schyf CJ, et al. (1999) Studies on the pyrrolinone metabolites derived from the tobacco alkaloid 1-methyl-2-(3-pyridinyl)pyrrole (beta-nicotyrine). Chemical Research in Toxicology. 12: 508-12
Palmer SL, Mabic S, Castagnoli N. (1997) Probing the active sites of monoamine oxidase A and B with 1,4-disubstituted tetrahydropyridine substrates and inactivators. Journal of Medicinal Chemistry. 40: 1982-9
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