Raymond G. Booth

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pharmaceutical Chemistry, Pharmacology, Biochemistry
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"Raymond Booth"
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Publications

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McGlynn RP, Cui M, Brems B, et al. (2023) Development of 2-Aminotetralin-Type Serotonin 5-HT Agonists: Molecular Determinants for Selective Binding and Signaling at 5-HT, 5-HT, 5-HT, and 5-HT Receptors. Acs Chemical Neuroscience. 15: 357-370
Fragola NR, Brems BM, Mukherjee M, et al. (2023) Conformationally Selective 2-Aminotetralin Ligands Targeting the alpha2A- and alpha2C-Adrenergic Receptors. Acs Chemical Neuroscience
Saraf TS, McGlynn RP, Bhatavdekar OM, et al. (2022) FPT, a 2-Aminotetralin, Is a Potent Serotonin 5-HT, 5-HT, and 5-HT Receptor Agonist That Modulates Cortical Electroencephalogram Activity in Adult Knockout Mice. Acs Chemical Neuroscience. 13: 3629-3640
Casey AB, Cui M, Booth RG, et al. (2022) "Selective" serotonin 5-HT receptor antagonists. Biochemical Pharmacology. 200: 115028
Casey AB, Mukherjee M, McGlynn RP, et al. (2021) A new class of serotonin 5-HT /5-HT receptor inverse agonists: Synthesis, molecular modeling, in vitro and in vivo pharmacology of novel 2-aminotetralins. British Journal of Pharmacology
Rdova-Sintjago TC, Villa N, Canal C, et al. (2021) Human Serotonin 5-HT G Protein-Coupled Receptor Homology Model from the Adrenoceptor Structure: Ligand Docking and Mutagenesis Studies. International Journal of Quantum Chemistry. 112
Armstrong JL, Casey AB, Saraf TS, et al. (2020) ()-5-(2'-Fluorophenyl)-,-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine, a Serotonin Receptor Modulator, Possesses Anticonvulsant, Prosocial, and Anxiolytic-like Properties in an Knockout Mouse Model of Fragile X Syndrome and Autism Spectrum Disorder. Acs Pharmacology & Translational Science. 3: 509-523
Perry CK, Casey AB, Felsing DE, et al. (2019) Synthesis of novel 5-substituted-2-aminotetralin analogs: 5-HT and 5-HT G protein-coupled receptor affinity, 3D-QSAR and molecular modeling. Bioorganic & Medicinal Chemistry. 115262
Felsing DE, Canal CE, Booth RG. (2019) Ligand-directed serotonin 5-HT receptor desensitization, β-arrestin recruitment, and sensitization. European Journal of Pharmacology
Mongeau E, Yuan G, Minden Z, et al. (2017) Homology Modeling Inspired Synthesis of 5-HT2A Receptor Inhibitors: A Diazepine Analogue of the Atypical Antipsychotic JL13. Central Nervous System Agents in Medicinal Chemistry
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