Alan D. Frankel

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Area:
Biochemistry
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Parents

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Carl O. Pabo grad student
Hamilton O. Smith grad student
Gary Keith Ackers grad student 1983 Johns Hopkins (Physics Tree)
 (Sequence-specific recognition of DNA by the Hinfi restriction endonuclease.)

Children

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Chandreyee Das grad student UCSF
Bernhard J. Walberer grad student 2000 UCSF
Alan C. Cheng grad student 2002 UCSF
Stephen G. Landt grad student 2004 UCSF
Alexander W. Pastuszak grad student 2006 UCSF
Matthew D. Daugherty grad student 2009 UCSF
Jason D. Fernandes grad student 2013 UCSF
David Scott Booth grad student 2007-2014 UCSF
Robert Nakamura post-doc 1999- UCSF
Kazuo Harada post-doc 1998
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Publications

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Gordon DE, Jang GM, Bouhaddou M, et al. (2020) A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature
Gordon DE, Watson A, Roguev A, et al. (2020) A Quantitative Genetic Interaction Map of HIV Infection. Molecular Cell
Hüttenhain R, Xu J, Burton LA, et al. (2019) ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection. Cell Host & Microbe
Jayaraman B, Fernandes JD, Yang S, et al. (2019) Highly Mutable Linker Regions Regulate HIV-1 Rev Function and Stability. Scientific Reports. 9: 5139
Dai Y, Wynn J, Peralta A, et al. (2018) Discovery of a Branched Peptide that Recognizes the Rev Response Element (RRE) RNA and Blocks HIV-1 Replication. Journal of Medicinal Chemistry
Faust TB, Li Y, Bacon CW, et al. (2018) The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation. Elife. 7
Faust TB, Binning JM, Gross JD, et al. (2017) Making Sense of Multifunctional Proteins: Human Immunodeficiency Virus Type 1 Accessory and Regulatory Proteins and Connections to Transcription. Annual Review of Virology. 4: 241-260
Nakamura RL, Burlingame MA, Yang S, et al. (2017) Identification and optimization of thienopyridine carboxamides as inhibitors of HIV regulatory complexes. Antimicrobial Agents and Chemotherapy
Faust TB, Li Y, Jang GM, et al. (2017) PJA2 ubiquitinates the HIV-1 Tat protein with atypical chain linkages to activate viral transcription. Scientific Reports. 7: 45394
Fernandes JD, Faust TB, Strauli NB, et al. (2016) Functional Segregation of Overlapping Genes in HIV. Cell. 167: 1762-1773.e12
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