Chris Dealwis
Affiliations: | The University of Tennessee, Knoxville, TN, United States |
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Children
Sign in to add trainee| Tomoaki Uchiki | grad student | 2004 | University of Tennessee |
| Brad C. Bennett | grad student | 2005 | University of Tennessee |
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Publications
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| Wan Q, Bennett BC, Wymore T, et al. (2021) Capturing the Catalytic Proton of Dihydrofolate Reductase: Implications for General Acid-Base Catalysis. Acs Catalysis. 11: 5873-5884 |
| Knappenberger AJ, Mohammed FA, Viswanathan R, et al. (2016) Nucleoside analog triphosphates allosterically regulate human ribonucleotide reductase and identify chemical determinants that drive substrate specificity. Biochemistry |
| Wan Q, Bennett BC, Wilson MA, et al. (2014) Toward resolving the catalytic mechanism of dihydrofolate reductase using neutron and ultrahigh-resolution X-ray crystallography. Proceedings of the National Academy of Sciences of the United States of America. 111: 18225-30 |
| Wan Q, Kovalevsky AY, Wilson MA, et al. (2014) Preliminary joint X-ray and neutron protein crystallographic studies of ecDHFR complexed with folate and NADP+. Acta Crystallographica. Section F, Structural Biology Communications. 70: 814-8 |
| Ahmad MF, Wan Q, Jha S, et al. (2012) Evaluating the therapeutic potential of a non-natural nucleotide that inhibits human ribonucleotide reductase. Molecular Cancer Therapeutics. 11: 2077-86 |
| Wan Q, Ahmad MF, Fairman J, et al. (2011) X-ray crystallography and isothermal titration calorimetry studies of the Salmonella zinc transporter ZntB. Structure (London, England : 1993). 19: 700-10 |
| Miyagi M, Wan Q, Ahmad MF, et al. (2011) Histidine hydrogen-deuterium exchange mass spectrometry for probing the microenvironment of histidine residues in dihydrofolate reductase. Plos One. 6: e17055 |
| Sun D, Xu H, Wijerathna SR, et al. (2009) Structure-Based Design, Synthesis, and Evaluation of 2'-(2-Hydroxyethyl)-2'-deoxyadenosine and the 5'-Diphosphate Derivative as Ribonucleotide Reductase Inhibitors. Chemmedchem. 4: 1649-56 |
| Gardberg A, Dice L, Pridgen K, et al. (2009) Structures of Aβ-related peptide-monoclonal antibody complexes Biochemistry. 48: 5210-5217 |
| Bennett BC, Wan Q, Ahmad MF, et al. (2009) X-ray structure of the ternary MTX.NADPH complex of the anthrax dihydrofolate reductase: a pharmacophore for dual-site inhibitor design. Journal of Structural Biology. 166: 162-71 |