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Curt M. Horvath

Affiliations: 
Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Molecular Biology, Cell Biology, Biochemistry
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"Curt Horvath"
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Parents

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Children

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Joe F. Lau grad student 2002 Mount Sinai School of Medicine
Jason J. Rodriguez grad student 2005 Mount Sinai School of Medicine
Christina M. Ulane grad student 2005 Mount Sinai School of Medicine

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Publications

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Philips RL, Wang Y, Cheon H, et al. (2022) The JAK-STAT pathway at 30: Much learned, much more to do. Cell. 185: 3857-3876
Parisien JP, Lenoir JJ, Alvarado G, et al. (2021) The Human STAT2 Coiled-Coil Domain Contains a Degron for Zika Virus Interferon Evasion. Journal of Virology. JVI0130121
Quicke KM, Kim KY, Horvath CM, et al. (2019) RNA Helicase LGP2 Negatively Regulates RIG-I Signaling by Preventing TRIM25-Mediated Caspase Activation and Recruitment Domain Ubiquitination. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research
Au-Yeung N, Horvath CM. (2018) Transcriptional and chromatin regulation in interferon and innate antiviral gene expression. Cytokine & Growth Factor Reviews. 44: 11-17
Saleiro D, Blyth GT, Kosciuczuk EM, et al. (2018) IFN-γ-inducible antiviral responses require ULK1-mediated activation of MLK3 and ERK5. Science Signaling. 11
Mandhana R, Horvath CM. (2018) Sendai Virus Infection Induces Expression of Novel RNAs in Human Cells. Scientific Reports. 8: 16815
Au-Yeung N, Horvath CM. (2018) Histone H2A.Z Suppression of Interferon-Stimulated Transcription and Antiviral Immunity Is Modulated by GCN5 and BRD2. Iscience. 6: 68-82
Mandhana R, Qian LK, Horvath CM. (2018) Constitutively Active MDA5 Proteins Are Inhibited by Paramyxovirus V Proteins. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 38: 319-332
Parisien JP, Lenoir JJ, Mandhana R, et al. (2018) RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling. Embo Reports
Pollpeter D, Parsons M, Sobala AE, et al. (2017) Deep sequencing of HIV-1 reverse transcripts reveals the multifaceted antiviral functions of APOBEC3G. Nature Microbiology
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