Andrew J. McDougal, Ph.D.
Affiliations: | 2000 | Texas A & M University, College Station, TX, United States |
Area:
Toxicology, OncologyGoogle:
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Parents
Sign in to add mentor| Stephen Safe | grad student | 2000 | Texas A & M | |
| (Aryl hydrocarbon receptor-based antiestrogens as treatments for breast cancer.) | ||||
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| Duan R, Xie W, Li X, et al. (2002) Estrogen regulation of c-fos gene expression through phosphatidylinositol-3-kinase-dependent activation of serum response factor in MCF-7 breast cancer cells. Biochemical and Biophysical Research Communications. 294: 384-94 |
| Safe S, McDougal A. (2002) Mechanism of action and development of selective aryl hydrocarbon receptor modulators for treatment of hormone-dependent cancers (Review). International Journal of Oncology. 20: 1123-8 |
| McDougal A, Gupta MS, Morrow D, et al. (2001) Methyl-substituted diindolylmethanes as inhibitors of estrogen-induced growth of T47D cells and mammary tumors in rats. Breast Cancer Research and Treatment. 66: 147-57 |
| McDougal A, Sethi Gupta M, Ramamoorthy K, et al. (2000) Inhibition of carcinogen-induced rat mammary tumor growth and other estrogen-dependent responses by symmetrical dihalo-substituted analogs of diindolylmethane. Cancer Letters. 151: 169-79 |
| Safe S, Qin C, McDougal A. (1999) Development of selective aryl hydrocarbon receptor modulators for treatment of breast cancer. Expert Opinion On Investigational Drugs. 8: 1385-96 |
| Ramamoorthy K, Gupta MS, Sun G, et al. (1999) 3,3'4,4'-Tetrachlorobiphenyl exhibits antiestrogenic and antitumorigenic activity in the rodent uterus and mammary cells and in human breast cancer cells. Carcinogenesis. 20: 115-23 |
| Gupta M, McDougal A, Safe S. (1998) Estrogenic and antiestrogenic activities of 16alpha- and 2-hydroxy metabolites of 17beta-estradiol in MCF-7 and T47D human breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 67: 413-9 |
| Safe S, Wang F, Porter W, et al. (1998) Ah receptor agonists as endocrine disruptors: antiestrogenic activity and mechanisms. Toxicology Letters. 102: 343-7 |
| Chen I, McDougal A, Wang F, et al. (1998) Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane. Carcinogenesis. 19: 1631-9 |
| McDougal A, Safe S. (1998) Induction of 16alpha-/2-hydroxyestrone metabolite ratios in MCF-7 cells by pesticides, carcinogens, and antiestrogens does not predict mammary carcinogens. Environmental Health Perspectives. 106: 203-6 |