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Wen Xie, Ph.D.

Affiliations: 
2001 Texas A & M University, College Station, TX, United States 
Area:
Toxicology, Molecular Biology
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"Wen Xie"
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Stephen H. Safe grad student 2001 Texas A & M
 (Hormonal regulation of genes involved in purine and pyrimidine biosynthesis and metabolism in human breast cancer cells.)

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Publications

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Duan R, Xie W, Li X, et al. (2002) Estrogen regulation of c-fos gene expression through phosphatidylinositol-3-kinase-dependent activation of serum response factor in MCF-7 breast cancer cells. Biochemical and Biophysical Research Communications. 294: 384-94
Xie W, Duan R, Safe S. (2001) Activation of adenosine deaminase in MCF-7 cells through IGF-estrogen receptor alpha crosstalk. Journal of Molecular Endocrinology. 26: 217-28
Duan R, Xie W, Burghardt RC, et al. (2001) Estrogen receptor-mediated activation of the serum response element in MCF-7 cells through MAPK-dependent phosphorylation of Elk-1. The Journal of Biological Chemistry. 276: 11590-8
Xie W, Duan R, Chen I, et al. (2000) Transcriptional Activation of Thymidylate Synthase by 17β-Estradiol in MCF-7 Human Breast Cancer Cells. Endocrinology. 141: 2439-2449
Xie W, Barwick JL, Simon CM, et al. (2000) Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR. Genes & Development. 14: 3014-23
Xie W, Duan R, Chen I, et al. (2000) Transcriptional activation of thymidylate synthase by 17beta-estradiol in MCF-7 human breast cancer cells. Endocrinology. 141: 2439-49
Xie W, Duan R, Safe S. (1999) Estrogen Induces Adenosine Deaminase Gene Expression in MCF-7 Human Breast Cancer Cells: Role of Estrogen Receptor-Sp1 Interactions* *This work was supported by the National Institutes of Health (Grant CA-76636), the Welch Foundation, and the Texas Agricultural Experiment Station. Endocrinology. 140: 219-227
Xie W, Duan R, Safe S. (1999) Estrogen induces adenosine deaminase gene expression in MCF-7 human breast cancer cells: role of estrogen receptor-Sp1 interactions. Endocrinology. 140: 219-27
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