Donald F. Senear
Affiliations: | University of California, Irvine, Irvine, CA |
Area:
Molecular Biology, Biochemistry, Microbiology BiologyGoogle:
"Donald Senear"Children
Sign in to add traineeRobert Todd Batey | research assistant | 1989-1990 | UC Irvine (Chemistry Tree) |
Allison K. Holt | grad student | 2008 | UC Irvine |
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Publications
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Holt AK, Senear DF. (2013) The cooperative binding energetics of CytR and cAMP receptor protein support a quantitative model of differential activation and repression of CytR-regulated class III Escherichia coli promoters. Biochemistry. 52: 8209-18 |
Wallentine BD, Wang Y, Tretyachenko-Ladokhina V, et al. (2013) Structures of oncogenic, suppressor and rescued p53 core-domain variants: mechanisms of mutant p53 rescue. Acta Crystallographica. Section D, Biological Crystallography. 69: 2146-56 |
Moody CL, Tretyachenko-Ladokhina V, Laue TM, et al. (2011) Multiple conformations of the cytidine repressor DNA-binding domain coalesce to one upon recognition of a specific DNA surface. Biochemistry. 50: 6622-32 |
Holt AK, Senear DF. (2010) An unusual pattern of CytR and CRP binding energetics at Escherichia coli cddP suggests a unique blend of class I and class II mediated activation. Biochemistry. 49: 432-42 |
Moody CL, Tretyachenko-Ladokhina V, Senear DF, et al. (2010) Structure and Dynamics of the Cytidine Repressor DNA-Binding Domain Biophysical Journal. 98: 660a |
Tan YH, Chen YM, Ye X, et al. (2009) Molecular mechanisms of functional rescue mediated by P53 tumor suppressor mutations. Biophysical Chemistry. 145: 37-44 |
Senear DF, Tretyachenko-Ladokhina V, Opel ML, et al. (2007) Pressure dissociation of integration host factor-DNA complexes reveals flexibility-dependent structural variation at the protein-DNA interface. Nucleic Acids Research. 35: 1761-72 |
Aeling KA, Steffen NR, Johnson M, et al. (2007) DNA deformation energy as an indirect recognition mechanism in protein-DNA interactions. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 4: 117-25 |
Aeling KA, Opel ML, Steffen NR, et al. (2006) Indirect recognition in sequence-specific DNA binding by Escherichia coli integration host factor: the role of DNA deformation energy. The Journal of Biological Chemistry. 281: 39236-48 |
Tretyachenko-Ladokhina V, Cocco MJ, Senear DF. (2006) Flexibility and adaptability in binding of E. coli cytidine repressor to different operators suggests a role in differential gene regulation. Journal of Molecular Biology. 362: 271-86 |