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James B. Flanegan

Affiliations: 
University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Biochemistry
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"James Flanegan"
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Parents

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Children

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Lynn S. Silvestri grad student 2001 UF Gainesville
Christy K. Jurgens grad student 2002 UF Gainesville
Jessica M. Parilla grad student 2005 UF Gainesville
Shane B. Claggett grad student 2008 UF Gainesville
Allyn R. Spear grad student 2009 UF Gainesville

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Publications

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Spear A, Ogram SA, Morasco BJ, et al. (2015) Viral precursor protein P3 and its processed products perform discrete and essential functions in the poliovirus RNA replication complex. Virology. 485: 492-501
Ogram SA, Boone CD, McKenna R, et al. (2014) Amiloride inhibits the initiation of Coxsackievirus and poliovirus RNA replication by inhibiting VPg uridylylation. Virology. 464: 87-97
Ogram SA, Flanegan JB. (2011) Non-template functions of viral RNA in picornavirus replication. Current Opinion in Virology. 1: 339-46
Ogram SA, Spear A, Sharma N, et al. (2010) The 5'CL-PCBP RNP complex, 3' poly(A) tail and 2A(pro) are required for optimal translation of poliovirus RNA. Virology. 397: 14-22
Sharma N, Ogram SA, Morasco BJ, et al. (2009) Functional role of the 5' terminal cloverleaf in Coxsackievirus RNA replication. Virology. 393: 238-49
Spear A, Sharma N, Flanegan JB. (2008) Protein-RNA tethering: the role of poly(C) binding protein 2 in poliovirus RNA replication. Virology. 374: 280-91
Jurgens CK, Barton DJ, Sharma N, et al. (2006) 2Apro is a multifunctional protein that regulates the stability, translation and replication of poliovirus RNA. Virology. 345: 346-57
Silvestri LS, Parilla JM, Morasco BJ, et al. (2006) Relationship between poliovirus negative-strand RNA synthesis and the length of the 3' poly(A) tail. Virology. 345: 509-19
Sharma N, O'Donnell BJ, Flanegan JB. (2005) 3'-Terminal sequence in poliovirus negative-strand templates is the primary cis-acting element required for VPgpUpU-primed positive-strand initiation. Journal of Virology. 79: 3565-77
Morasco BJ, Sharma N, Parilla J, et al. (2003) Poliovirus cre(2C)-dependent synthesis of VPgpUpU is required for positive- but not negative-strand RNA synthesis. Journal of Virology. 77: 5136-44
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