M L. Koschinsky
Affiliations: | Queen's University, Canada, Kingston, Ontario, Canada |
Area:
Molecular Biology, BiochemistryGoogle:
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Publications
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| Doerfler AM, Park SH, Assini JM, et al. (2022) disruption with AAV-CRISPR potently lowers plasma apo(a) in transgenic mouse model: A proof-of-concept study. Molecular Therapy. Methods & Clinical Development. 27: 337-351 |
| Koschinsky ML, Boffa MB. (2022) Oxidized phospholipid modification of lipoprotein(a): Epidemiology, biochemistry and pathophysiology. Atherosclerosis. 349: 92-100 |
| Clark JR, Gemin M, Youssef A, et al. (2022) Sortilin enhances secretion of apolipoprotein(a) through effects on apolipoprotein B secretion and promotes uptake of lipoprotein(a). Journal of Lipid Research. 100216 |
| Gonen A, Yang X, Yeang C, et al. (2020) Generation and characterization of LPA-KIV9, a murine monoclonal antibody binding a single site on apolipoprotein(a). Journal of Lipid Research |
| Romagnuolo R, DeMarco K, Scipione CA, et al. (2018) Apolipoprotein(a) inhibits the conversion of Glu-plasminogen to Lys-plasminogen on the surface of vascular endothelial and smooth muscle cells. Thrombosis Research. 169: 1-7 |
| Romagnuolo R, Scipione CA, Marcovina SM, et al. (2017) Roles of the low density lipoprotein receptor and related receptors in inhibition of lipoprotein(a) internalization by proprotein convertase subtilisin/kexin type 9. Plos One. 12: e0180869 |
| Scipione CA, McAiney JT, Simard DJ, et al. (2017) Characterization of the I4399M variant of apolipoprotein(a): Implications for altered prothrombotic properties of lipoprotein(a). Journal of Thrombosis and Haemostasis : Jth |
| Romagnuolo R, Scipione CA, Boffa MB, et al. (2015) Lipoprotein(a) catabolism is regulated by proprotein convertase subtilisin/kexin type 9 through the low density lipoprotein receptor. The Journal of Biological Chemistry. 290: 11649-62 |
| Romagnuolo R, Marcovina SM, Boffa MB, et al. (2014) Inhibition of plasminogen activation by apo(a): role of carboxyl-terminal lysines and identification of inhibitory domains in apo(a). Journal of Lipid Research. 55: 625-34 |
| Leibundgut G, Scipione C, Yin H, et al. (2013) Determinants of binding of oxidized phospholipids on apolipoprotein (a) and lipoprotein (a). Journal of Lipid Research. 54: 2815-30 |