Yi Sheng, Ph.D.

Affiliations: 
2004 University of Toronto, Toronto, ON, Canada 
Area:
Molecular Biology, Biochemistry
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"Yi Sheng"
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Andrew Bognar grad student 2004 University of Toronto
 (Structural and functional studies of folylpolyglutamate synthetase.)
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Publications

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Liu J, Li Y, Lin B, et al. (2017) HBL1 Is a Human Long Noncoding RNA that Modulates Cardiomyocyte Development from Pluripotent Stem Cells by Counteracting MIR1. Developmental Cell. 43: 372
Liu J, Li Y, Lin B, et al. (2017) HBL1 Is a Human Long Noncoding RNA that Modulates Cardiomyocyte Development from Pluripotent Stem Cells by Counteracting MIR1. Developmental Cell. 42: 333-348.e5
Egorova O, Mis M, Sheng Y. (2014) A site-directed mutagenesis study of the MdmX RING domain. Biochemical and Biophysical Research Communications. 447: 696-701
Sarkari F, Wheaton K, La Delfa A, et al. (2013) Ubiquitin-specific protease 7 is a regulator of ubiquitin-conjugating enzyme UbE2E1. The Journal of Biological Chemistry. 288: 16975-85
Sheng Y, Hong JH, Doherty R, et al. (2012) A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Molecular & Cellular Proteomics : McP. 11: 329-41
Hao Z, Duncan GS, Su YW, et al. (2012) The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis. The Journal of Experimental Medicine. 209: 173-86
Hakem A, Bohgaki M, Lemmers B, et al. (2011) Role of Pirh2 in mediating the regulation of p53 and c-Myc. Plos Genetics. 7: e1002360
Shloush J, Vlassov JE, Engson I, et al. (2011) Structural and functional comparison of the RING domains of two p53 E3 ligases, Mdm2 and Pirh2. The Journal of Biological Chemistry. 286: 4796-808
Sarkari F, Sheng Y, Frappier L. (2010) USP7/HAUSP promotes the sequence-specific DNA binding activity of p53. Plos One. 5: e13040
Ko S, Kang GB, Song SM, et al. (2010) Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity. The Journal of Biological Chemistry. 285: 36070-80
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