Ronald P. Trible, Ph.D.

Affiliations: 
2006 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Molecular Biology, Biochemistry, Virology Biology
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"Ronald Trible"
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Thomas E. Smithgall grad student 2006 University of Pittsburgh
 (Selective activation of Src family kinases by the HIV-1 Nef protein.)
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Publications

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Band VI, Ibegbu C, Kaur SP, et al. (2014) Induction of human plasmablasts during infection with antibiotic-resistant nosocomial bacteria. The Journal of Antimicrobial Chemotherapy. 69: 1830-3
Trible RP, Narute P, Emert-Sedlak LA, et al. (2013) Discovery of a diaminoquinoxaline benzenesulfonamide antagonist of HIV-1 Nef function using a yeast-based phenotypic screen. Retrovirology. 10: 135
Trible R, Edgerton N, Hayek S, et al. (2013) Antiretroviral therapy-associated coccidioidal meningitis. Emerging Infectious Diseases. 19: 163-5
Trible RP, Emert-Sedlak L, Wales TE, et al. (2007) Allosteric loss-of-function mutations in HIV-1 Nef from a long-term non-progressor. Journal of Molecular Biology. 374: 121-9
Mitchell JL, Trible RP, Emert-Sedlak LA, et al. (2007) Functional characterization and conformational analysis of the Herpesvirus saimiri Tip-C484 protein. Journal of Molecular Biology. 366: 1282-93
Trible RP, Emert-Sedlak L, Smithgall TE. (2006) HIV-1 Nef selectively activates Src family kinases Hck, Lyn, and c-Src through direct SH3 domain interaction. The Journal of Biological Chemistry. 281: 27029-38
Lerner EC, Trible RP, Schiavone AP, et al. (2005) Activation of the Src family kinase Hck without SH3-linker release. The Journal of Biological Chemistry. 280: 40832-7
Schaefer TM, Bell I, Pfeifer ME, et al. (2002) The conserved process of TCR/CD3 complex down-modulation by SIV Nef is mediated by the central core, not endocytic motifs. Virology. 302: 106-22
Bell I, Schaefer TM, Trible RP, et al. (2001) Down-modulation of the costimulatory molecule, CD28, is a conserved activity of multiple SIV Nefs and is dependent on histidine 196 of Nef. Virology. 283: 148-58
Bunnell SC, Kapoor V, Trible RP, et al. (2001) Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT. Immunity. 14: 315-29
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