Joseck M. Muhuhi, Ph.D.
Affiliations: | 2006 | Wayne State University, Detroit, MI, United States |
Area:
Organic ChemistryGoogle:
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Parents
Sign in to add mentor| Mark Spaller | grad student | 2006 | Wayne State | |
| (Design and development of bioactive compounds: Targeting HIV -1 protease, neuronal PDZ, and anticancer analogs of heterolignans.) | ||||
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Publications
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| Allen LJ, Muhuhi JM, Bland DC, et al. (2014) Mild fluorination of chloropyridines with in situ generated anhydrous tetrabutylammonium fluoride Journal of Organic Chemistry. 79: 5827-5833 |
| Allen LJ, Lee SH, Cheng Y, et al. (2014) Developing efficient nucleophilic fluorination methods and application to substituted picolinate esters Organic Process Research and Development. 18: 1045-1054 |
| Yedidi RS, Muhuhi JM, Liu Z, et al. (2013) Design, synthesis and evaluation of a potent substrate analog inhibitor identified by scanning Ala/Phe mutagenesis, mimicking substrate co-evolution, against multidrug-resistant HIV-1 protease. Biochemical and Biophysical Research Communications. 438: 703-8 |
| Denmark SE, Liu JH, Muhuhi JM. (2011) Stereocontrolled total syntheses of isodomoic acids G and H via a unified strategy. The Journal of Organic Chemistry. 76: 201-15 |
| Denmark SE, Muhuhi JM. (2010) Development of a general, sequential, ring-closing metathesis/intramolecular cross-coupling reaction for the synthesis of polyunsaturated macrolactones. Journal of the American Chemical Society. 132: 11768-78 |
| Denmark SE, Liu JH, Muhuhi JM. (2009) Total syntheses of isodomoic acids G and H. Journal of the American Chemical Society. 131: 14188-9 |
| Denmark SE, Smith RC, Chang WT, et al. (2009) Cross-coupling reactions of aromatic and heteroaromatic silanolates with aromatic and heteroaromatic halides. Journal of the American Chemical Society. 131: 3104-18 |
| Denmark SE, Smith RC, Chang WT, et al. (2009) ChemInform Abstract: Cross-Coupling Reactions of Aromatic and Heteroaromatic Silanolates with Aromatic and Heteroaromatic Halides. Cheminform. 40 |
| Muhuhi J, Spaller MR. (2006) Expanding the synthetic method and structural diversity potential for the intramolecular Aza Diels-Alder cyclization. The Journal of Organic Chemistry. 71: 5515-26 |
| Spaller M, Muhuhi J. (2006) Synthesis of Tetrahydroquinolines via an Intramolecular Aza-Diels-Alder Reaction Synfacts. 2006: 1107-1107 |