Ho-Jin Chang, Ph.D.

Affiliations: 
2004 Universite Laval (Canada) 
Area:
Animal Physiology Biology, Biochemistry
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"Ho-Jin Chang"
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Sheng-Xiang Lin grad student 2004 Universite Laval (Canada)
 (Human ADT/DHEA sulfotransferase: A combined study of enzymology and crystallography.)
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Poirier D, Chang HJ, Azzi A, et al. (2006) Estrone and estradiol C-16 derivatives as inhibitors of type 1 17beta-hydroxysteroid dehydrogenase. Molecular and Cellular Endocrinology. 248: 236-8
Chang HJ, Shi R, Rehse P, et al. (2004) Identifying androsterone (ADT) as a cognate substrate for human dehydroepiandrosterone sulfotransferase (DHEA-ST) important for steroid homeostasis: structure of the enzyme-ADT complex. The Journal of Biological Chemistry. 279: 2689-96
Zhou M, Qiu W, Chang HJ, et al. (2002) Purification, crystallization and preliminary X-ray diffraction results of human 17beta-hydroxysteroid dehydrogenase type 5. Acta Crystallographica. Section D, Biological Crystallography. 58: 1048-50
Huang YW, Pineau I, Chang HJ, et al. (2001) Critical residues for the specificity of cofactors and substrates in human estrogenic 17beta-hydroxysteroid dehydrogenase 1: variants designed from the three-dimensional structure of the enzyme. Molecular Endocrinology (Baltimore, Md.). 15: 2010-20
Zhou M, Rehse P, Chang HJ, et al. (2001) Crystallization and preliminary crystallographic results of apo and complex forms of human dehydroepiandrosterone sulfotransferase. Acta Crystallographica. Section D, Biological Crystallography. 57: 1630-3
Chang HJ, Zhou M, Lin SX. (2001) Human dehydroepiandrosterone sulfotransferase: purification and characterization of a recombinant protein. The Journal of Steroid Biochemistry and Molecular Biology. 77: 159-65
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