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Kris T. Huang, Ph.D.

Affiliations: 
2006 Wake Forest University, Winston-Salem, NC, United States 
Area:
Medical Biophysics, Biomedical Engineering
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Daniel B. Kim-Shapiro grad student 2006 Wake Forest
 (The role of hemoglobin, nitrite, and nitric oxide in hypoxic vasodilation.)

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Huang KT, Huang Z, Kim-Shapiro DB. (2007) Nitric oxide red blood cell membrane permeability at high and low oxygen tension. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 16: 209-16
Huang KT, Azarov I, Basu S, et al. (2006) Lack of allosterically controlled intramolecular transfer of nitric oxide from the heme to cysteine in the beta subunit of hemoglobin. Blood. 107: 2602-4
Huang KT, Azarov I, Huang Z, et al. (2006) P042. Nitric oxide red blood cell membrane permeability depends on oxygen tension Nitric Oxide. 14: 31
Azarov I, Huang KT, Basu S, et al. (2005) Nitric oxide scavenging by red blood cells as a function of hematocrit and oxygenation. The Journal of Biological Chemistry. 280: 39024-32
Huang Z, Shiva S, Kim-Shapiro DB, et al. (2005) Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control. The Journal of Clinical Investigation. 115: 2099-107
Jeffers A, Xu X, Huang KT, et al. (2005) Hemoglobin mediated nitrite activation of soluble guanylyl cyclase. Comparative Biochemistry and Physiology. Part a, Molecular & Integrative Physiology. 142: 130-5
Huang KT, Keszler A, Patel N, et al. (2005) The reaction between nitrite and deoxyhemoglobin. Reassessment of reaction kinetics and stoichiometry. The Journal of Biological Chemistry. 280: 31126-31
Kim-Shapiro DB, Azarov I, Huang KT, et al. (2005) Hematocrit and Oxygen Dependence of Nitric Oxide Scavenging by Red Blood Cells. Blood. 106: 205-205
Cosby K, Partovi KS, Crawford JH, et al. (2003) Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation. Nature Medicine. 9: 1498-505
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