Kuan-Ming Chen, Ph.D.

2010 Biochemistry, Molecular Bio, and Biophysics University of Minnesota, Twin Cities, Minneapolis, MN 
General Biophysics, Immunology, Biochemistry
"Kuan-Ming Chen"
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Hiroshi Matsuo grad student 2010 UMN
 (Structural studies of the deaminase domain of the human HIV-1 restriction protein APOBE 3G.)
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Harjes S, Solomon WC, Li M, et al. (2013) Impact of H216 on the DNA binding and catalytic activities of the HIV restriction factor APOBEC3G. Journal of Virology. 87: 7008-14
Dewan V, Liu T, Chen KM, et al. (2012) Cyclic peptide inhibitors of HIV-1 capsid-human lysyl-tRNA synthetase interaction. Acs Chemical Biology. 7: 761-9
Harjes E, Gross PJ, Chen KM, et al. (2009) An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model. Journal of Molecular Biology. 389: 819-32
Chen KM, Harjes E, Gross PJ, et al. (2008) Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G. Nature. 452: 116-9
Devany M, Kappes F, Chen KM, et al. (2008) Solution NMR structure of the N-terminal domain of the human DEK protein. Protein Science : a Publication of the Protein Society. 17: 205-15
Chen KM, Martemyanova N, Lu Y, et al. (2007) Extensive mutagenesis experiments corroborate a structural model for the DNA deaminase domain of APOBEC3G. Febs Letters. 581: 4761-6
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