Hemali P. Phatnani, Ph.D.

Affiliations: 
2004 Duke University, Durham, NC 
Area:
Biochemistry
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"Hemali Phatnani"
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Parents

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Arno L. Greenleaf grad student 2004 Duke
 (Expanding the functional repertoire of RNA polymerase II and CTD kinase I: Novel phospho -CTD associating proteins in the yeast proteome.)
Tom Maniatis post-doc 2006-2013 Columbia
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Publications

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Zhang Y, Chen K, Sloan SA, et al. (2014) An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 11929-47
Chiu IM, Morimoto ET, Goodarzi H, et al. (2013) A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model. Cell Reports. 4: 385-401
Bilican B, Serio A, Barmada SJ, et al. (2013) Comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells". Science Translational Medicine. 5: 188le2
Serio A, Bilican B, Barmada SJ, et al. (2013) Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy. Proceedings of the National Academy of Sciences of the United States of America. 110: 4697-702
Phatnani HP, Guarnieri P, Friedman BA, et al. (2013) Intricate interplay between astrocytes and motor neurons in ALS. Proceedings of the National Academy of Sciences of the United States of America. 110: E756-65
Bilican B, Serio A, Barmada SJ, et al. (2012) Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability. Proceedings of the National Academy of Sciences of the United States of America. 109: 5803-8
Möller A, Xie SQ, Hosp F, et al. (2012) Proteomic analysis of mitotic RNA polymerase II reveals novel interactors and association with proteins dysfunctional in disease. Molecular & Cellular Proteomics : McP. 11: M111.011767
Bartkowiak B, Liu P, Phatnani HP, et al. (2010) CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1. Genes & Development. 24: 2303-16
Wu J, Phatnani HP, Hsieh TS, et al. (2010) The phosphoCTD-interacting domain of Topoisomerase I. Biochemical and Biophysical Research Communications. 397: 117-9
Bennett CB, Westmoreland TJ, Verrier CS, et al. (2008) Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction. Plos One. 3: e1448
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