Michele E. Wisniewski, Ph.D.

Affiliations: 
2001 University of Rochester, Rochester, NY 
Area:
Biochemistry, Molecular Biology
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Robert A. Bambara grad student 2001 Rochester
 (The mechanism of the polymerase independent mode of RNase H cleavage by HIV-1 reverse transcriptase.)
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Publications

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Livezey K, Kaplan S, Wisniewski M, et al. (2013) A new generation of food-borne pathogen detection based on ribosomal RNA. Annual Review of Food Science and Technology. 4: 313-25
Wisniewski M, Chen Y, Balakrishnan M, et al. (2002) Substrate requirements for secondary cleavage by HIV-1 reverse transcriptase RNase H. The Journal of Biological Chemistry. 277: 28400-10
Archer RH, Wisniewski M, Bambara RA, et al. (2001) The Y181C mutant of HIV-1 reverse transcriptase resistant to nonnucleoside reverse transcriptase inhibitors alters the size distribution of RNase H cleavages. Biochemistry. 40: 4087-95
Wisniewski M, Balakrishnan M, Palaniappan C, et al. (2000) Unique progressive cleavage mechanism of HIV reverse transcriptase RNase H. Proceedings of the National Academy of Sciences of the United States of America. 97: 11978-83
Wisniewski M, Balakrishnan M, Palaniappan C, et al. (2000) The sequential mechanism of HIV reverse transcriptase RNase H. The Journal of Biological Chemistry. 275: 37664-71
Wisniewski M, Palaniappan C, Fu Z, et al. (1999) Mutations in the primer grip region of HIV reverse transcriptase can increase replication fidelity. The Journal of Biological Chemistry. 274: 28175-84
Palaniappan C, Kim JK, Wisniewski M, et al. (1998) Control of initiation of viral plus strand DNA synthesis by HIV reverse transcriptase. The Journal of Biological Chemistry. 273: 3808-16
Palaniappan C, Wisniewski M, Jacques PS, et al. (1997) Mutations within the primer grip region of HIV-1 reverse transcriptase result in loss of RNase H function. The Journal of Biological Chemistry. 272: 11157-64
Palaniappan C, Wisniewski M, Wu W, et al. (1996) Misincorporation by HIV-1 reverse transcriptase promotes recombination via strand transfer synthesis. The Journal of Biological Chemistry. 271: 22331-8
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