David L. Carbone, Ph.D.

Affiliations: 
2005 University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Toxicology, General Biophysics
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Dennis R. Petersen grad student 2005 University of Colorado, Denver
 (Effects of the lipid peroxidation product 4-hydroxy-2-nonenal on protein degradation and refolding pathways.)
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Publications

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Roede JR, Carbone DL, Doorn JA, et al. (2008) In vitro and in silico characterization of peroxiredoxin 6 modified by 4-hydroxynonenal and 4-oxononenal. Chemical Research in Toxicology. 21: 2289-99
Sampey BP, Carbone DL, Doorn JA, et al. (2007) 4-Hydroxy-2-nonenal adduction of extracellular signal-regulated kinase (Erk) and the inhibition of hepatocyte Erk-Est-like protein-1-activating protein-1 signal transduction. Molecular Pharmacology. 71: 871-83
Carbone DL, Doorn JA, Kiebler Z, et al. (2005) Cysteine modification by lipid peroxidation products inhibits protein disulfide isomerase. Chemical Research in Toxicology. 18: 1324-31
Carbone DL, Doorn JA, Kiebler Z, et al. (2005) Modification of heat shock protein 90 by 4-hydroxynonenal in a rat model of chronic alcoholic liver disease. The Journal of Pharmacology and Experimental Therapeutics. 315: 8-15
Carbone DL, Doorn JA, Kiebler Z, et al. (2004) Inhibition of Hsp72-mediated protein refolding by 4-hydroxy-2-nonenal. Chemical Research in Toxicology. 17: 1459-67
Carbone DL, Doorn JA, Petersen DR. (2004) 4-Hydroxynonenal regulates 26S proteasomal degradation of alcohol dehydrogenase. Free Radical Biology & Medicine. 37: 1430-9
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