Kelsie M. Bernot, Ph.D.

Affiliations: 
2005 Johns Hopkins University, Baltimore, MD 
Area:
Biochemistry
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"Kelsie Bernot"
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Pierre A. Coulombe grad student 2005 Johns Hopkins
 (Mechanistic insight into keratin intermediate filament function.)
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Publications

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Wang Y, Liu Y, Tang F, et al. (2014) Echinomycin protects mice against relapsed acute myeloid leukemia without adverse effect on hematopoietic stem cells. Blood. 124: 1127-35
Bernot KM, Nemer JS, Santhanam R, et al. (2013) Eradicating acute myeloid leukemia in a Mll(PTD/wt):Flt3(ITD/wt) murine model: a path to novel therapeutic approaches for human disease. Blood. 122: 3778-83
Zorko NA, Yanes DA, Lewis WC, et al. (2013) Abstract 3849: The partial tandem duplication of Mll (Mll PTD) is a gain-of-function in the absence of Mll wildtype (Mll WT) in adult mouse hematopoiesis. Cancer Research. 73: 3849-3849
Bernot KM, Nemer JS, Santhanam R, et al. (2013) Abstract 3249: Targeting the miR29b/Sp1/Dnmt pathway for curative therapy in Mll-PTD/Flt3-ITD acute myeloid leukemia. Cancer Research. 73: 3249-3249
Zhang Y, Yan X, Sashida G, et al. (2012) Stress hematopoiesis reveals abnormal control of self-renewal, lineage bias, and myeloid differentiation in Mll partial tandem duplication (Mll-PTD) hematopoietic stem/progenitor cells. Blood. 120: 1118-29
Zorko NA, Bernot KM, Whitman SP, et al. (2012) Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias. Blood. 120: 1130-6
Balagopalan L, Ashwell BA, Bernot KM, et al. (2011) Enhanced T-cell signaling in cells bearing linker for activation of T-cell (LAT) molecules resistant to ubiquitylation. Proceedings of the National Academy of Sciences of the United States of America. 108: 2885-90
Zhang Y, Yan X, Sashida G, et al. (2011) MLL-PTD Causes Hypomorph Condition of CBF Complex (RUNX1/CBFβ) and Predisposes the Abnormal Hematopoietic Stem and Progenitor Cells (HSPCs) to Clonal Expansion Blood. 118: 2801-2801
Zorko N, Whitman SP, Bernot K, et al. (2010) The Mll PTD and Flt3 ITD Double Knock-In Mouse Develops Acute Leukemia and Recapitulates Phenotypic, Molecular and Epigenetic Characteristics of the Counterpart Human Acute Myeloid Leukemia Blood. 116: 150-150
Patino-Lopez G, Dong X, Ben-Aissa K, et al. (2008) Rab35 and its GAP EPI64C in T cells regulate receptor recycling and immunological synapse formation. The Journal of Biological Chemistry. 283: 18323-30
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