Michael J. Trnka, Ph.D.

Affiliations: 
2004 University of Washington, Seattle, Seattle, WA 
Area:
Biochemistry
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"Michael Trnka"
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William F. Trager grad student 2004 University of Washington
 (Photoaffinity labeling of cytochrome P450s with imidazole -tethered benzophenone compounds.)
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Publications

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Liu Y, Trnka MJ, Guan S, et al. (2020) A Novel Mechanism For NF-κB Activation Via IκB Aggregation: Implications For Hepatic Mallory-Denk-Body Induced Inflammation. Molecular & Cellular Proteomics : McP
von Appen A, LaJoie D, Johnson IE, et al. (2020) LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation. Nature. 582: 115-118
Sanulli S, Trnka MJ, Dharmarajan V, et al. (2019) HP1 reshapes nucleosome core to promote heterochromatin phase separation. Nature
Iacobucci C, Piotrowski C, Aebersold R, et al. (2019) The First Community-Wide, Comparative Cross-linking Mass Spectrometry Study. Analytical Chemistry
Trnka M, Pellarin R, Robinson P. (2019) Role of Integrative Structural Biology in Understanding Transcriptional Initiation. Methods (San Diego, Calif.)
Longbotham JE, Chio CM, Dharmarajan V, et al. (2019) Histone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodeling. Nature Communications. 10: 94
Gamarra N, Johnson SL, Trnka MJ, et al. (2018) The nucleosomal acidic patch relieves auto-inhibition by the ISWI remodeler SNF2h. Elife. 7
Larson AG, Elnatan D, Keenen MM, et al. (2017) Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin. Nature
Zhou CY, Stoddard CI, Johnston JB, et al. (2017) Regulation of Rvb1/Rvb2 by a Domain within the INO80 Chromatin Remodeling Complex Implicates the Yeast Rvbs as Protein Assembly Chaperones. Cell Reports. 19: 2033-2044
Robinson PJ, Trnka MJ, Bushnell DA, et al. (2016) Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex. Cell. 166: 1411-1422.e16
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