David Turgeon, Ph.D.

Affiliations: 
2002 Universite Laval (Canada) 
Area:
Animal Physiology Biology, Molecular Biology
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Alain Belanger grad student 2002 Universite Laval (Canada)
 (Clonage et caracterisation des UDP-glucuronosyltransferases de la sous-famille 2B (UGT2B) dans les tissus extrahepatiques.)
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Publications

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Turgeon D, Carrier JS, Chouinard S, et al. (2003) Glucuronidation activity of the UGT2B17 enzyme toward xenobiotics. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 670-6
Turgeon D, Chouinard S, Belanger P, et al. (2003) Glucuronidation of arachidonic and linoleic acid metabolites by human UDP-glucuronosyltransferases. Journal of Lipid Research. 44: 1182-91
Girard C, Barbier O, Turgeon D, et al. (2002) Isolation and characterization of the monkey UGT2B30 gene that encodes a uridine diphosphate-glucuronosyltransferase enzyme active on mineralocorticoid, glucocorticoid, androgen and oestrogen hormones. The Biochemical Journal. 365: 213-22
Turgeon D, Carrier JB, Le Vesque ER, et al. (2001) Relative Enzymatic Activity, Protein Stability, and Tissue Distribution of Human Steroid-Metabolizing UGT2B Subfamily Members**This work was supported by the Medical Research Council of Canada, the Fonds de la Recherche en Santé du Québec, and Endorecherche. Endocrinology. 142: 778-787
Lévesque E, Turgeon D, Carrier JS, et al. (2001) Isolation and characterization of the UGT2B28 cDNA encoding a novel human steroid conjugating UDP-glucuronosyltransferase. Biochemistry. 40: 3869-81
Turgeon D, Carrier JS, Lévesque E, et al. (2001) Relative enzymatic activity, protein stability, and tissue distribution of human steroid-metabolizing UGT2B subfamily members. Endocrinology. 142: 778-87
Carrier JS, Turgeon D, Journault K, et al. (2000) Isolation and characterization of the human UGT2B7 gene. Biochemical and Biophysical Research Communications. 272: 616-21
Barbier O, Turgeon D, Girard C, et al. (2000) 3'-azido-3'-deoxythimidine (AZT) is glucuronidated by human UDP-glucuronosyltransferase 2B7 (UGT2B7). Drug Metabolism and Disposition: the Biological Fate of Chemicals. 28: 497-502
Turgeon D, Carrier JS, Lévesque E, et al. (2000) Isolation and characterization of the human UGT2B15 gene, localized within a cluster of UGT2B genes and pseudogenes on chromosome 4. Journal of Molecular Biology. 295: 489-504
Hum DW, Bélanger A, Lévesque E, et al. (1999) Characterization of UDP-glucuronosyltransferases active on steroid hormones. The Journal of Steroid Biochemistry and Molecular Biology. 69: 413-23
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