Nicole Hajicek, Ph.D.

Affiliations: 
2010 University of Illinois at Chicago, Health Sciences Center, Chicago, IL 60612, United States 
Area:
Pharmacology
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"Nicole Hajicek"
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Parents

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Tohru Kozasa grad student 2010 University of Illinois at Chicago, Health Sciences Center
 (Regulation of p115RhoGEF by Galpha13.)
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Publications

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Siraliev-Perez E, Hoffmann R, Stariha J, et al. (2020) Dynamics of allosteric activation in PLC‐γ isozymes The Faseb Journal. 34: 1-1
Hajicek N, Keith NC, Siraliev-Perez E, et al. (2019) Structural basis for the activation of PLC-γ isozymes by phosphorylation and cancer-associated mutations. Elife. 8
Hajicek N, Keith NC, Siraliev-Perez E, et al. (2019) Author response: Structural basis for the activation of PLC-γ isozymes by phosphorylation and cancer-associated mutations Elife
Hajicek N, Keith NC, Siraliev-Perez E, et al. (2019) Structural basis for the activation of PLC-gamma isozymes by phosphorylation and cancer-associated mutations. Elife. 8
Huang W, Wang X, Endo-Streeter S, et al. (2017) A membrane-associated, fluorogenic reporter for mammalian phospholipase C isozymes. The Journal of Biological Chemistry
Hajicek N, Charpentier TH, Rush JR, et al. (2013) Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes. Biochemistry. 52: 4810-9
Huang W, Barrett M, Hajicek N, et al. (2013) Small molecule inhibitors of phospholipase C from a novel high-throughput screen. The Journal of Biological Chemistry. 288: 5840-8
Hajicek N, Charpentier TH, Rush JR, et al. (2013) Autoinhibition and Phosphorylation-Induced Activation of Phospholipase C-gamma Isozymes. Biochemistry. 52: 4810-4819
Kozasa T, Hajicek N, Chow CR, et al. (2011) Signalling mechanisms of RhoGTPase regulation by the heterotrimeric G proteins G12 and G13. Journal of Biochemistry. 150: 357-69
Hajicek N, Kukimoto-Niino M, Mishima-Tsumagari C, et al. (2011) Identification of critical residues in G(alpha)13 for stimulation of p115RhoGEF activity and the structure of the G(alpha)13-p115RhoGEF regulator of G protein signaling homology (RH) domain complex. The Journal of Biological Chemistry. 286: 20625-36
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