Nicole Hajicek, Ph.D.

2010 University of Illinois at Chicago, Health Sciences Center 
"Nicole Hajicek"
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Tohru Kozasa grad student 2010 University of Illinois at Chicago, Health Sciences Center
 (Regulation of p115RhoGEF by Galpha13.)
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Kozasa T, Hajicek N, Chow CR, et al. (2011) Signalling mechanisms of RhoGTPase regulation by the heterotrimeric G proteins G12 and G13. Journal of Biochemistry. 150: 357-69
Hajicek N, Kukimoto-Niino M, Mishima-Tsumagari C, et al. (2011) Identification of critical residues in G(alpha)13 for stimulation of p115RhoGEF activity and the structure of the G(alpha)13-p115RhoGEF regulator of G protein signaling homology (RH) domain complex. The Journal of Biological Chemistry. 286: 20625-36
Jernigan KK, Cselenyi CS, Thorne CA, et al. (2010) Gbetagamma activates GSK3 to promote LRP6-mediated beta-catenin transcriptional activity. Science Signaling. 3: ra37
Suzuki N, Hajicek N, Kozasa T. (2009) Regulation and physiological functions of G12/13-mediated signaling pathways. Neuro-Signals. 17: 55-70
Suzuki N, Tsumoto K, Hajicek N, et al. (2009) Activation of leukemia-associated RhoGEF by Galpha13 with significant conformational rearrangements in the interface. The Journal of Biological Chemistry. 284: 5000-9
Hajicek N, Kozasa T. (2008) G protein alpha 13 Afcs-Nature Molecule Pages
Kreutz B, Hajicek N, Yau DM, et al. (2007) Distinct regions of Galpha13 participate in its regulatory interactions with RGS homology domain-containing RhoGEFs. Cellular Signalling. 19: 1681-9
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