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Jenny J. Zhang, Ph.D.

Affiliations: 
2002 Medical University of South Carolina, Charleston, SC, United States 
Area:
Biochemistry, Molecular Biology
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Julie Chao grad student 2002 MUSC
 (Protective roles of tissue kallikrein in salt -induced cardiac, renal and cerebral injury.)

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Bledsoe G, Shen B, Yao Y, et al. (2006) Reversal of renal fibrosis, inflammation, and glomerular hypertrophy by kallikrein gene delivery. Human Gene Therapy. 17: 545-55
Zhang JJ, Bledsoe G, Kato K, et al. (2004) Tissue kallikrein attenuates salt-induced renal fibrosis by inhibition of oxidative stress. Kidney International. 66: 722-32
Agata J, Zhang JJ, Chao J, et al. (2003) Adrenomedullin gene delivery inhibits neointima formation in rat artery after balloon angioplasty. Regulatory Peptides. 112: 115-20
Chao J, Kato K, Zhang JJ, et al. (2001) Human adrenomedullin gene delivery protects against cardiovascular remodeling and renal injury. Peptides. 22: 1731-7
Zhang JJ, Yoshida H, Chao L, et al. (2000) Human adrenomedullin gene delivery protects against cardiac hypertrophy, fibrosis, and renal damage in hypertensive dahl salt-sensitive rats. Human Gene Therapy. 11: 1817-27
Yoshida H, Zhang JJ, Chao L, et al. (2000) Kallikrein gene delivery attenuates myocardial infarction and apoptosis after myocardial ischemia and reperfusion. Hypertension. 35: 25-31
Zhang JJ, Wang C, Lin KF, et al. (1999) Human tissue kallikrein attenuates hypertension and secretes into circulation and urine after intramuscular gene delivery in hypertensive rats. Clinical and Experimental Hypertension (New York, N.Y. : 1993). 21: 1145-60
Zhang JJ, Chao L, Chao J. (1999) Adenovirus-mediated kallikrein gene delivery reduces aortic thickening and stroke-induced death rate in Dahl salt-sensitive rats. Stroke; a Journal of Cerebral Circulation. 30: 1925-31; discussion
Chao J, Zhang JJ, Lin KF, et al. (1998) Adenovirus-mediated kallikrein gene delivery reverses salt-induced renal injury in Dahl salt-sensitive rats. Kidney International. 54: 1250-60
Chao J, Zhang JJ, Lin KF, et al. (1998) Human kallikrein gene delivery attenuates hypertension, cardiac hypertrophy, and renal injury in Dahl salt-sensitive rats. Human Gene Therapy. 9: 21-31
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