Nicole Brufatto, Ph.D.
Affiliations: | 2003 | Queen's University, Canada, Kingston, Ontario, Canada |
Area:
BiochemistryGoogle:
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Parents
Sign in to add mentor| Michael E. Nesheim | grad student | 2003 | Queen's University, Canada | |
| (The enzymology and regulation of prothrombinase.) | ||||
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Publications
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| Bukys MA, Blum MA, Kim PY, et al. (2005) Incorporation of factor Va into prothrombinase is required for coordinated cleavage of prothrombin by factor Xa. The Journal of Biological Chemistry. 280: 27393-401 |
| Dennis MW, Downey C, Brufatto N, et al. (2004) Prothrombinase enhancement through quantitative and qualitative changes affecting very low density lipoprotein in complex with C-reactive protein Thrombosis and Haemostasis. 91: 522-530 |
| Orfeo T, Brufatto N, Nesheim ME, et al. (2004) The factor V activation paradox. The Journal of Biological Chemistry. 279: 19580-91 |
| Schneider M, Brufatto N, Neill E, et al. (2004) Activated thrombin-activatable fibrinolysis inhibitor reduces the ability of high molecular weight fibrin degradation products to protect plasmin from antiplasmin. The Journal of Biological Chemistry. 279: 13340-5 |
| Brufatto N, Ward A, Nesheim ME. (2003) Factor Xa is highly protected from antithrombin-fondaparinux and antithrombin-enoxaparin when incorporated into the prothrombinase complex. Journal of Thrombosis and Haemostasis : Jth. 1: 1258-63 |
| Brufatto N, Nesheim ME. (2003) Analysis of the kinetics of prothrombin activation and evidence that two equilibrating forms of prothrombinase are involved in the process. The Journal of Biological Chemistry. 278: 6755-64 |
| Nesheim M, Samis J, Walker J, et al. (2002) Lipoprotein-complexed C-reactive protein and the biphasic transmittance waveform in critically ill patients Blood Reviews. 16: S15-22 |
| Toh CH, Samis J, Downey C, et al. (2002) Biphasic transmittance waveform in the APTT coagulation assay is due to the formation of a Ca ++-dependent complex of C-reactive protein with very-low-density lipoprotein and is a novel marker of impending disseminated intravascular coagulation Blood. 100: 2522-2529 |
| Brufatto N, Nesheim ME. (2001) The use of prothrombin(S525C) labeled with fluorescein to directly study the inhibition of prothrombinase by antithrombin during prothrombin activation. The Journal of Biological Chemistry. 276: 17663-71 |