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Joe F. Lau, Ph.D.

Affiliations: 
2002 Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Molecular Biology, Biochemistry, Cell Biology
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Curt M. Horvath grad student 2002 Mount Sinai School of Medicine
 (Analysis of the subcellular distribution, assembly, and transcriptional activity of the trimeric, IFN-activated transcription complex ISGF3.)

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Kraus TA, Lau JF, Parisien JP, et al. (2003) A hybrid IRF9-STAT2 protein recapitulates interferon-stimulated gene expression and antiviral response. The Journal of Biological Chemistry. 278: 13033-8
Lau JF, Nusinzon I, Burakov D, et al. (2003) Role of metazoan mediator proteins in interferon-responsive transcription. Molecular and Cellular Biology. 23: 620-8
Parisien JP, Lau JF, Horvath CM. (2002) STAT2 acts as a host range determinant for species-specific paramyxovirus interferon antagonism and simian virus 5 replication. Journal of Virology. 76: 6435-41
Lau JF, Horvath CM. (2002) Mechanisms of Type I interferon cell signaling and STAT-mediated transcriptional responses. The Mount Sinai Journal of Medicine, New York. 69: 156-68
Parisien JP, Lau JF, Rodriguez JJ, et al. (2002) Selective STAT protein degradation induced by paramyxoviruses requires both STAT1 and STAT2 but is independent of alpha/beta interferon signal transduction. Journal of Virology. 76: 4190-8
Parisien JP, Lau JF, Rodriguez JJ, et al. (2001) The V protein of human parainfluenza virus 2 antagonizes type I interferon responses by destabilizing signal transducer and activator of transcription 2. Virology. 283: 230-9
Lau JF, Parisien JP, Horvath CM. (2000) Interferon regulatory factor subcellular localization is determined by a bipartite nuclear localization signal in the DNA-binding domain and interaction with cytoplasmic retention factors. Proceedings of the National Academy of Sciences of the United States of America. 97: 7278-83
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