Adam B. Castoreno, Ph.D.

Affiliations: 
2005 Harvard University, Cambridge, MA, United States 
Area:
Cell Biology, Biochemistry
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"Adam Castoreno"
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Parents

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Axel Nohturfft grad student 2005 Harvard
 (Control of lipid synthesis and distribution during membrane biogenesis.)
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Publications

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Yang S, Imamura Y, Jenkins R, et al. (2016) Autophagy inhibition dysregulates TBK1 signaling and promotes pancreatic inflammation. Cancer Immunology Research
Kuo SY, Castoreno AB, Aldrich LN, et al. (2015) Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics. Proceedings of the National Academy of Sciences of the United States of America
Aldrich LN, Kuo SY, Castoreno AB, et al. (2015) Discovery of a Small-Molecule Probe for V-ATPase Function. Journal of the American Chemical Society. 137: 5563-8
Shaw SY, Tran K, Castoreno AB, et al. (2013) Selective modulation of autophagy, innate immunity, and adaptive immunity by small molecules. Acs Chemical Biology. 8: 2724-33
Castoreno AB, Eggert US. (2011) Small molecule probes of cellular pathways and networks. Acs Chemical Biology. 6: 86-94
Castoreno AB, Smurnyy Y, Torres AD, et al. (2010) Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis. Nature Chemical Biology. 6: 457-63
Atilla-Gokcumen GE, Castoreno AB, Sasse S, et al. (2010) Making the cut: the chemical biology of cytokinesis. Acs Chemical Biology. 5: 79-90
Trivedi V, Zhang SC, Castoreno AB, et al. (2006) Immunoglobulin G signaling activates lysosome/phagosome docking. Proceedings of the National Academy of Sciences of the United States of America. 103: 18226-31
Stockinger W, Zhang SC, Trivedi V, et al. (2006) Differential requirements for actin polymerization, calmodulin, and Ca2+ define distinct stages of lysosome/phagosome targeting. Molecular Biology of the Cell. 17: 1697-710
Castoreno AB, Wang Y, Stockinger W, et al. (2005) Transcriptional regulation of phagocytosis-induced membrane biogenesis by sterol regulatory element binding proteins. Proceedings of the National Academy of Sciences of the United States of America. 102: 13129-34
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