Lokesh Gakhar, Ph.D.

Affiliations: 
2003 University of Iowa, Iowa City, IA 
Area:
Structural Biology
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"Lokesh Gakhar"
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Parents

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John M. Wiencek grad student 2003 University of Iowa
 (Ice formation in flash cooled protein crystals.)
Paul McCray X (Bronchopulmonary Tree)
Ramaswamy Subramanian post-doc (Crystallography Tree)

Collaborators

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Christopher A. Ahern collaborator (Physics Tree)
Zeynep Akyol Ataman collaborator
Michael A. Apicella collaborator (Microtree)
Nikolai O. Artemyev collaborator
Jennifer A. Bartlett collaborator (Bronchopulmonary Tree)
Alexander G. Bassuk collaborator (Cell Biology Tree)
Ryan L. Boudreau collaborator (Neurotree)
Craig D. Ellermeier collaborator (Microtree)
Michael D. Feldkamp collaborator
Bret D. Freudenthal collaborator
Ernesto J. Fuentes collaborator
Jon C. Houtman collaborator
Chou-Long Huang collaborator (Neurotree)
Amnon Kohen collaborator
Damian Krysan collaborator (Microtree)
Vinit B. Mahajan collaborator (Cell Biology Tree)
Robert Piper collaborator (Cell Biology Tree)
Madeline A. Shea collaborator
Maria Spies collaborator
Mani Subramanian collaborator (E-Tree)
Ryan M. Summers collaborator (E-Tree)
Susan E. Tsutakawa collaborator
M. Todd Washington collaborator (Cell Biology Tree)
BETA: Related publications

Publications

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Honda M, Razzaghi M, Gaur P, et al. (2023) Human RAD52 double-ring remodels replication forks restricting fork reversal. Biorxiv : the Preprint Server For Biology
Sandouk A, Xu Z, Baruah S, et al. (2023) GRB2 dimerization mediated by SH2 domain-swapping is critical for T cell signaling and cytokine production. Scientific Reports. 13: 3505
Plapp BV, Gakhar L, Subramanian R. (2022) Dependence of crystallographic atomic displacement parameters on temperature (25-150 K) for complexes of horse liver alcohol dehydrogenase. Acta Crystallographica. Section D, Structural Biology. 78: 1221-1234
Weaver TM, Hoitsma NM, Spencer JJ, et al. (2022) Structural basis for APE1 processing DNA damage in the nucleosome. Nature Communications. 13: 5390
Pashkova N, Gakhar L, Yu L, et al. (2021) ANTH domains within CALM, HIP1R, and Sla2 recognize ubiquitin internalization signals. Elife. 10
Pashkova N, Yu L, Schnicker NJ, et al. (2021) Interactions of ubiquitin and CHMP5 with the V domain of HD-PTP reveals role for regulation of Vps4 ATPase. Molecular Biology of the Cell. mbcE21040219
Beattie SR, Schnicker NJ, Murante T, et al. (2020) Benzothiourea derivates target the secretory pathway of the human fungal pathogen Cryptococcus neoformans. Acs Infectious Diseases
Velez G, Sun YJ, Khan S, et al. (2020) Structural Insights into the Unique Activation Mechanisms of a Non-classical Calpain and Its Disease-Causing Variants. Cell Reports. 30: 881-892.e5
Pagano P, Guo Q, Ranasinghe C, et al. (2019) Oscillatory Active-site Motions Correlate with Kinetic Isotope Effects in Formate Dehydrogenase. Acs Catalysis. 9: 11199-11206
Sathyanarayanan N, Cannone G, Gakhar L, et al. (2019) Molecular basis for metabolite channeling in a ring opening enzyme of the phenylacetate degradation pathway. Nature Communications. 10: 4127
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